Structure–activity relationships for ruthenium and osmium anticancer agents–towards clinical development
SM Meier-Menches, C Gerner, W Berger… - Chemical Society …, 2018 - pubs.rsc.org
Anticancer metallodrugs based on ruthenium and osmium are among the most investigated
and advanced non-platinum metallodrugs. Inorganic drug discovery with these agents has …
and advanced non-platinum metallodrugs. Inorganic drug discovery with these agents has …
Hybrid organic− inorganic polyoxometalate compounds: from structural diversity to applications
A Dolbecq, E Dumas, CR Mayer, P Mialane - Chemical reviews, 2010 - ACS Publications
Polyoxometalates (POMs) are discrete anionic metaloxygen clusters which can be regarded
as soluble oxide fragments. They exhibit a great diversity of sizes, nuclearities, and shapes …
as soluble oxide fragments. They exhibit a great diversity of sizes, nuclearities, and shapes …
Organic dye-sensitized tandem photoelectrochemical cell for light driven total water splitting
Light driven water splitting was achieved by a tandem dye-sensitized photoelectrochemical
cell with two photoactive electrodes. The photoanode is constituted by an organic dye L0 as …
cell with two photoactive electrodes. The photoanode is constituted by an organic dye L0 as …
Ruthenium metallopharmaceuticals
MJ Clarke - Coordination Chemistry Reviews, 2002 - Elsevier
The well-developed synthetic chemistry of ruthenium, particularly with ammine, amine and
imine ligands, provides for many approaches to innovative new metallopharmaceuticals …
imine ligands, provides for many approaches to innovative new metallopharmaceuticals …
Arene ruthenium complexes as anticancer agents
G Süss-Fink - Dalton Transactions, 2010 - pubs.rsc.org
Neutral or cationic arene ruthenium complexes providing both hydrophilic as well as
hydrophobic properties due to the robustness of the ruthenium–arene unit hold a high …
hydrophobic properties due to the robustness of the ruthenium–arene unit hold a high …
The emergence of sulfoxides as efficient ligands in transition metal catalysis
Sulfoxides are capable of forming stable complexes with transition metals and there have
been many comprehensive studies into their binding properties. However, the use of …
been many comprehensive studies into their binding properties. However, the use of …
[PDF][PDF] Non-platinum chemotherapeutic metallopharmaceuticals
MJ Clarke, F Zhu, DR Frasca - Chemical Reviews, 1999 - academia.edu
Despite the resounding success of cisplatin and closely related platinum antitumor agents, 1-
3 the movement of other transition-metal antitumor agents toward the clinic has been …
3 the movement of other transition-metal antitumor agents toward the clinic has been …
Recent developments in ruthenium anticancer drugs
Interest in Ru anticancer drugs has been growing rapidly since NAMI-A ((ImH+)[RuIIICl4
(Im)(S-dmso)], where Im= imidazole and S-dmso= S-bound dimethylsulfoxide) or KP1019 …
(Im)(S-dmso)], where Im= imidazole and S-dmso= S-bound dimethylsulfoxide) or KP1019 …
Trans-effects in octahedral transition metal complexes
BJ Coe, SJ Glenwright - Coordination Chemistry Reviews, 2000 - Elsevier
An extensive survey of the occurrences and origins of both structural trans-effects (STEs)
and kinetic trans-effects (KTEs) in octahedral d-transition metal complexes is presented. This …
and kinetic trans-effects (KTEs) in octahedral d-transition metal complexes is presented. This …
Classical and non‐classical ruthenium‐based anticancer drugs: Towards targeted chemotherapy
Ruthenium‐based anticancer chemotherapies are making significant advances in clinical
trials. Until recently, the focus has been on coordination complexes, and mechanisms such …
trials. Until recently, the focus has been on coordination complexes, and mechanisms such …