Carotenoids and human health

AV Rao, LG Rao - Pharmacological research, 2007 - Elsevier
Oxidative stress is an important contributor to the risk of chronic diseases. Dietary guidelines
recommend increased consumption of fruits and vegetables to combat the incidence of …

[HTML][HTML] Oxidative stress in bone remodeling: role of antioxidants

V Domazetovic, G Marcucci, T Iantomasi… - Clinical Cases in …, 2017 - ncbi.nlm.nih.gov
ROS are highly reactive molecules which consist of a number of diverse chemical species,
including radical and non-radical oxygen species. Oxidative stress occurs as a result of an …

Oxidative stress and osteoporosis

JS Kimball, JP Johnson, DWA Carlson - JBJS, 2021 - journals.lww.com
Oxidative Stress and Osteoporosis : JBJS Oxidative Stress and Osteoporosis : JBJS JBJS Journal
Case Connector Reviews JBJS.org Surgical Techniques Open Access JOPA Log in Subscribe …

From estrogen-centric to aging and oxidative stress: a revised perspective of the pathogenesis of osteoporosis

SC Manolagas - Endocrine reviews, 2010 - academic.oup.com
Estrogen deficiency has been considered the seminal mechanism of osteoporosis in both
women and men, but epidemiological evidence in humans and recent mechanistic studies …

Glutathione dysregulation and the etiology and progression of human diseases

N Ballatori, SM Krance, S Notenboom, S Shi, K Tieu… - 2009 - degruyter.com
Glutathione (GSH) plays an important role in a multitude of cellular processes, including cell
differentiation, proliferation, and apoptosis, and as a result, disturbances in GSH …

Age-related changes in human bone marrow-derived mesenchymal stem cells: consequences for cell therapies

A Stolzing, E Jones, D Mcgonagle, A Scutt - Mechanisms of ageing and …, 2008 - Elsevier
Human mesenchymal stem cells (hMSC) represent a promising cell-based therapy for a
number of degenerative conditions. Understanding the effect of aging on hMSCs is crucial …

Estrogen deficiency and bone loss: an inflammatory tale

MN Weitzmann, R Pacifici - The Journal of clinical …, 2006 - Am Soc Clin Investig
Estrogen plays a fundamental role in skeletal growth and bone homeostasis in both men
and women. Although remarkable progress has been made in our understanding of how …

Oxidative stress in brain aging, neurodegenerative and vascular diseases: an overview

E Mariani, MC Polidori, A Cherubini… - Journal of Chromatography …, 2005 - Elsevier
According to the free radical theory, aging can be considered as a progressive, inevitable
process partially related to the accumulation of oxidative damage into biomolecules–nucleic …

Targeting aldehyde dehydrogenase 2: new therapeutic opportunities

CH Chen, JCB Ferreira, ER Gross… - Physiological …, 2014 - journals.physiology.org
A family of detoxifying enzymes called aldehyde dehydrogenases (ALDHs) has been a
subject of recent interest, as its role in detoxifying aldehydes that accumulate through …

Aging of mesenchymal stem cells

S Sethe, A Scutt, A Stolzing - Ageing research reviews, 2006 - Elsevier
The role of adult mesenchymal stem cells (MSC) in tissue maintenance and regeneration
has received significant attention of late. Questions arise to what extent these cells are either …