OBJECTIVE: To provide a systematic review of the relationship between age and leukocyte
telomere length (LTL) in adults. METHODS: Relevant studies were identified by a systematic …

The discovery of causative genetic mutations in affected family members has historically
dominated our understanding of neurodegenerative diseases such as Alzheimer's disease …

Telomere length (TL) has been associated with aging and mortality, but individual
differences are also influenced by genetic factors, with previous studies reporting heritability …

Genetic lesions that reduce telomerase activity inhibit stem cell replication and cause a
range of incurable diseases, including dyskeratosis congenita (DC) and pulmonary fibrosis …

Background Telomere length (TL) and its attrition are important indicators of physiological
stress and biological aging and hence may vary among individuals of the same age. This …

Although shortened telomeres were shown associated with several risk factors of diabetes,
there is lack of data on their relationship with mitochondrial dysfunction. Therefore, we …

Telomerase is of key importance for telomere maintenance, and variants of the genes
encoding its major subunits, telomerase reverse transcriptase (TERT) and telomerase RNA …

Results: In general, there were only a few significant results. However, total fat and SFA
intake (P= 0.04 and 0.01, respectively) were inversely associated with LTL in men adjusting …

Telomeres, noncoding hexameric tandem repeats located at the ends of chromosomes,
maintain chromosome stability and genome integrity. These guanine‐rich repeats are highly …

Telomere biology is associated with cancer initiation and prognosis. Collected data suggest
that blood cell telomere length (TL) can change over time, which may be related to …