Postmeiotic spermatids use a unique strategy to coordinate gene expression with
morphological transformation, in which transcription and translation take place at separate …

Emerging and re-emerging infectious diseases due to RNA viruses cause major negative
consequences for the quality of life, public health, and overall economic development. Most …

Ribosomes are complex ribozymes that interpret genetic information by translating
messenger RNA (mRNA) into proteins. Natural variation in ribosome composition has been …

The incorporation of machine learning methods into proteomics workflows improves the
identification of disease-relevant biomarkers and biological pathways. However, machine …

The MSstats R-Bioconductor family of packages is widely used for statistical analyses of
quantitative bottom-up mass spectrometry-based proteomic experiments to detect …

Despite major advancements in lung cancer treatment, long-term survival is still rare and a
deeper understanding of molecular phenotypes would allow the identification of specific …

Basal-like breast cancer (BLBC) is the most aggressive subtype of breast tumors with poor
prognosis and limited molecular-targeted therapy options. We show that BLBC cells have a …

Nanotechnology is employed across a wide range of antibacterial applications in clinical
settings, food, pharmaceutical and textile industries, water treatment and consumer goods …

In the rapidly moving proteomics field, a diverse patchwork of data analysis pipelines and
algorithms for data normalization and differential expression analysis is used by the …

Oncogenic KRAS mutations are absent in approximately 10% of patients with metastatic
pancreatic ductal adenocarcinoma (mPDAC) and may represent a subgroup of mPDAC with …