T cell migration, search strategies and mechanisms
T cell migration is essential for T cell responses; it allows for the detection of cognate antigen
at the surface of antigen-presenting cells and for interactions with other cells involved in the …
at the surface of antigen-presenting cells and for interactions with other cells involved in the …
Mechanisms and dynamics of T cell-mediated cytotoxicity in vivo
S Halle, O Halle, R Förster - Trends in immunology, 2017 - cell.com
Cytotoxic T lymphocytes (CTLs) are critical in the elimination of infected or malignant cells
and are emerging as a major therapeutic target. How CTLs recognize and kill harmful cells …
and are emerging as a major therapeutic target. How CTLs recognize and kill harmful cells …
NF-κB dynamics in the language of immune cells
Biological discovery has been driven by advances in throughput and resolution of analysis
technologies. They have also created an indelible bias for snapshot-based knowledge …
technologies. They have also created an indelible bias for snapshot-based knowledge …
Dynamic Multiplex tissue imaging in inflammation research
Inflammation is a highly dynamic process with immune cells that continuously interact with
each other and parenchymal components as they migrate through tissue. The dynamic …
each other and parenchymal components as they migrate through tissue. The dynamic …
Brain-on-a-chip model enables analysis of human neuronal differentiation and chemotaxis
Migration of neural progenitors in the complex tissue environment of the central nervous
system is not well understood. Progress in this area has the potential to drive breakthroughs …
system is not well understood. Progress in this area has the potential to drive breakthroughs …
New tools for immunologists: models of lymph node function from cells to tissues
The lymph node is a highly structured organ that mediates the body's adaptive immune
response to antigens and other foreign particles. Central to its function is the distinct spatial …
response to antigens and other foreign particles. Central to its function is the distinct spatial …
Guidelines for visualization and analysis of DC in tissues using multiparameter fluorescence microscopy imaging methods
F Bayerl, DA Bejarano, G Bertacchi… - European Journal of …, 2023 - Wiley Online Library
This article is part of the Dendritic Cell Guidelines article series, which provides a collection
of state‐of‐the‐art protocols for the preparation, phenotype analysis by flow cytometry …
of state‐of‐the‐art protocols for the preparation, phenotype analysis by flow cytometry …
Inflammatory chemokines direct and restrict leukocyte migration within live tissues as glycan-bound gradients
M Sarris, JB Masson, D Maurin, LM Van der Aa… - Current Biology, 2012 - cell.com
Chemokines are essential in many cell migration processes, including the recruitment of
leukocytes to sites of infection [1–3]. In the latter context, chemokines promote leukocyte …
leukocytes to sites of infection [1–3]. In the latter context, chemokines promote leukocyte …
Detection of rare antigen-presenting cells through T cell-intrinsic meandering motility, mediated by Myo1g
To mount an immune response, T lymphocytes must successfully search for foreign material
bound to the surface of antigen-presenting cells. How T cells optimize their chances of …
bound to the surface of antigen-presenting cells. How T cells optimize their chances of …