Bond-selective imaging by optically sensing the mid-infrared photothermal effect
Mid-infrared (IR) spectroscopic imaging using inherent vibrational contrast has been broadly
used as a powerful analytical tool for sample identification and characterization. However …
used as a powerful analytical tool for sample identification and characterization. However …
Mid-infrared photothermal microscopy: principle, instrumentation, and applications
Midinfrared photothermal (MIP) microscopy, also called optical photothermal infrared (O-
PTIR) microscopy, is an emerging tool for bond-selective chemical imaging of living …
PTIR) microscopy, is an emerging tool for bond-selective chemical imaging of living …
Using Fourier transform IR spectroscopy to analyze biological materials
IR spectroscopy is an excellent method for biological analyses. It enables the
nonperturbative, label-free extraction of biochemical information and images toward …
nonperturbative, label-free extraction of biochemical information and images toward …
Depth-resolved mid-infrared photothermal imaging of living cells and organisms with submicrometer spatial resolution
Chemical contrast has long been sought for label-free visualization of biomolecules and
materials in complex living systems. Although infrared spectroscopic imaging has come a …
materials in complex living systems. Although infrared spectroscopic imaging has come a …
Infrared spectroscopic laser scanning confocal microscopy for whole-slide chemical imaging
Chemical imaging, especially mid-infrared spectroscopic microscopy, enables label-free
biomedical analyses while achieving expansive molecular sensitivity. However, its slow …
biomedical analyses while achieving expansive molecular sensitivity. However, its slow …
High-resolution, high-contrast mid-infrared imaging of fresh biological samples with ultraviolet-localized photoacoustic microscopy
Mid-infrared (MIR) microscopy provides rich chemical and structural information about
biological samples, without staining. Conventionally, the long MIR wavelength severely …
biological samples, without staining. Conventionally, the long MIR wavelength severely …
Label-free biomedical optical imaging
Label-free optical imaging employs natural and non-destructive approaches to visualize
biomedical samples for both biological assays and clinical diagnosis. At present, this field …
biomedical samples for both biological assays and clinical diagnosis. At present, this field …
Digital histopathology by infrared spectroscopic imaging
R Bhargava - Annual Review of Analytical Chemistry, 2023 - annualreviews.org
Infrared (IR) spectroscopic imaging records spatially resolved molecular vibrational spectra,
enabling a comprehensive measurement of the chemical makeup and heterogeneity of …
enabling a comprehensive measurement of the chemical makeup and heterogeneity of …
Quantum cascade lasers (QCLs) in biomedical spectroscopy
Quantum cascade lasers (QCL) are the first room temperature semiconductor laser source
for the mid-IR spectral region, triggering substantial development for the advancement of …
for the mid-IR spectral region, triggering substantial development for the advancement of …
Attenuated total reflection Fourier-transform infrared (ATR-FTIR) imaging of tissues and live cells
KLA Chan, SG Kazarian - Chemical Society Reviews, 2016 - pubs.rsc.org
FTIR spectroscopic imaging is a label-free, non-destructive and chemically specific
technique that can be utilised to study a wide range of biomedical applications such as …
technique that can be utilised to study a wide range of biomedical applications such as …