Polymersome-based protein drug delivery–quo vadis?

MG Gouveia, JP Wesseler, J Ramaekers… - Chemical Society …, 2023 - pubs.rsc.org
Protein-based therapeutics are an attractive alternative to established therapeutic
approaches and represent one of the fastest growing families of drugs. While many of these …

Design, functionalization strategies and biomedical applications of targeted biodegradable/biocompatible polymer-based nanocarriers for drug delivery

J Nicolas, S Mura, D Brambilla, N Mackiewicz… - Chemical Society …, 2013 - pubs.rsc.org
Design and functionalization strategies for multifunctional nanocarriers (eg, nanoparticles,
micelles, polymersomes) based on biodegradable/biocompatible polymers intended to be …

Imaging and drug delivery using theranostic nanoparticles

SM Janib, AS Moses, JA MacKay - Advanced drug delivery reviews, 2010 - Elsevier
Nanoparticle technologies are significantly impacting the development of both therapeutic
and diagnostic agents. At the intersection between treatment and diagnosis, interest has …

Functional polypeptide and hybrid materials: Precision synthesis via α-amino acid N-carboxyanhydride polymerization and emerging biomedical applications

C Deng, J Wu, R Cheng, F Meng, HA Klok… - Progress in Polymer …, 2014 - Elsevier
Polypeptides derived from naturally occurring α-amino acids have emerged as a unique and
versatile family of bio-inspired biomaterials that can be tailor-made for varying biomedical …

Polymeric micelles of biodegradable diblock copolymers: enhanced encapsulation of hydrophobic drugs

YHA Hussein, M Youssry - Materials, 2018 - mdpi.com
Polymeric micelles are potentially efficient in encapsulating and performing the controlled
release of various hydrophobic drug molecules. Understanding the fundamental …

Hyaluronic acid-based nanomaterials for cancer therapy

JH Kim, MJ Moon, DY Kim, SH Heo, YY Jeong - Polymers, 2018 - mdpi.com
Hyaluronic acid (HA) is a nonsulfated glycosaminoglycan and a major component of the
extracellular matrix. HA is overexpressed by numerous tumor cells, especially tumor …

Polymeric vesicles in biomedical applications

RP Brinkhuis, FPJT Rutjes, JCM van Hest - Polymer Chemistry, 2011 - pubs.rsc.org
Polymeric vesicles, or polymersomes, are nano-to micrometre sized polymeric capsules with
a bilayered membrane. Applications of these vesicles are foreseen in nanomedicine, in vivo …

“Click” reactions in polysaccharide modification

X Meng, KJ Edgar - Progress in Polymer Science, 2016 - Elsevier
Polysaccharide chemistry is enjoying accelerating development thanks to advances in
synthetic techniques, biochemistry and solvents, which enable polysaccharide materials to …

Polysaccharide–peptide conjugates: a versatile material platform for biomedical applications

HQ Song, Y Fan, Y Hu, G Cheng… - Advanced Functional …, 2021 - Wiley Online Library
Natural polymers, such as polysaccharides and proteins, have been widely studied for
numerous biomedical applications because of their bioactivity, natural origin, and …

Carbohydrate-based amphiphilic nano delivery systems for cancer therapy

K Liu, X Jiang, P Hunziker - Nanoscale, 2016 - pubs.rsc.org
Nanoparticles (NPs) are novel drug delivery systems that have been attracting more and
more attention in recent years, and have been used for the treatment of cancer, infection …