The brain structure, inflammatory, and genetic mechanisms mediate the association between physical frailty and depression

R Jiang, S Noble, M Rosenblatt, W Dai, J Ye… - Nature …, 2024‏ - nature.com
Cross-sectional studies have demonstrated strong associations between physical frailty and
depression. However, the evidence from prospective studies is limited. Here, we analyze …

Associations between grip strength, brain structure, and mental health in> 40,000 participants from the UK Biobank

R Jiang, ML Westwater, S Noble, M Rosenblatt, W Dai… - BMC medicine, 2022‏ - Springer
Background Grip strength is a widely used and well-validated measure of overall health that
is increasingly understood to index risk for psychiatric illness and neurodegeneration in …

Multimodal fusion of brain imaging data: Methods and applications

N Luo, W Shi, Z Yang, M Song, T Jiang - Machine Intelligence Research, 2024‏ - Springer
Neuroimaging data typically include multiple modalities, such as structural or functional
magnetic resonance imaging, diffusion tensor imaging, and positron emission tomography …

Associations of physical frailty with health outcomes and brain structure in 483 033 middle-aged and older adults: a population-based study from the UK Biobank

R Jiang, S Noble, J Sui, K Yoo, M Rosenblatt… - The Lancet Digital …, 2023‏ - thelancet.com
Background Physical frailty is a state of increased vulnerability to stressors and is associated
with serious health issues. However, how frailty affects and is affected by numerous other …

[HTML][HTML] Searching reproducible brain features using NeuroMark: templates for different age populations and imaging modalities

Z Fu, I Batta, L Wu, A Abrol, O Agcaoglu, MS Salman… - Neuroimage, 2024‏ - Elsevier
A primary challenge to the data-driven analysis is the balance between poor generalizability
of population-based research and characterizing more subject-, study-and population …

Changes in EEG activity and cognition related to physical activity in older adults: a systematic review

LM Rodríguez-Serrano, M Wöbbeking-Sánchez… - Life, 2024‏ - mdpi.com
Aging is generally associated with a decline in important cognitive functions that can be
observed in EEG. Physical activity in older adults should be considered one of the main …

Functional connectivity uniqueness and variability? Linkages with cognitive and psychiatric problems in children

Z Fu, J Liu, MS Salman, J Sui, VD Calhoun - Nature Mental Health, 2023‏ - nature.com
Brain functional connectivity (FC) derived from functional magnetic resonance imaging has
been serving as a potential 'fingerprint'for adults. However, cross-scan variation of FC can …

Elevated C-reactive protein mediates the liver-brain axis: a preliminary study

R Jiang, J Wu, M Rosenblatt, W Dai, RX Rodriguez… - …, 2023‏ - thelancet.com
Background Chronic liver diseases of all etiologies exist along a spectrum with varying
degrees of hepatic fibrosis. Despite accumulating evidence implying associations between …

Functional and structural alterations of dorsal attention network in preclinical and early‐stage Alzheimer's disease

H Wu, Y Song, X Yang, S Chen, H Ge… - CNS Neuroscience …, 2023‏ - Wiley Online Library
Objectives Subjective cognitive decline (SCD) and amnestic mild cognitive impairment
(aMCI) are known as the preclinical and early stage of Alzheimer's disease (AD). The dorsal …

Cross‐cohort replicable resting‐state functional connectivity in predicting symptoms and cognition of schizophrenia

C Zhao, R Jiang, J Bustillo, P Kochunov… - Human Brain …, 2024‏ - Wiley Online Library
Schizophrenia (SZ) is a debilitating mental illness characterized by adolescence or early
adulthood onset of psychosis, positive and negative symptoms, as well as cognitive …