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Making natural products from renewable feedstocks: back to the roots?
J Kühlborn, J Groß, T Opatz - Natural Product Reports, 2020 - pubs.rsc.org
Covering: up to mid-2019 This review highlights the utilization of biomass-derived building
blocks in the total synthesis of natural products. An overview over several renewable …
blocks in the total synthesis of natural products. An overview over several renewable …
Morphine alkaloids: History, biology, and synthesis
This chapter provides a short overview of the history of morphine since it's isolation by
Sertürner in 1805. The biosynthesis of the title alkaloid as well as all total and formal …
Sertürner in 1805. The biosynthesis of the title alkaloid as well as all total and formal …
Pharmaceutically relevant (hetero) cyclic compounds and natural products from lignin-derived monomers: present and perspectives
A Afanasenko, K Barta - Iscience, 2021 - cell.com
Lignin, the richest source of renewable aromatics on the planet, is an intriguing raw material
for the construction of value-added aromatics. In the past decade, much progress has been …
for the construction of value-added aromatics. In the past decade, much progress has been …
The role of biocatalysis in the asymmetric synthesis of alkaloids–an update
Alkaloids are a group of natural products with interesting pharmacological properties and a
long history of medicinal application. Their complex molecular structures have fascinated …
long history of medicinal application. Their complex molecular structures have fascinated …
Intramolecular heck reaction in total synthesis of natural products: an update
This review highlights the application of intramolecular Heck reaction in total synthesis of
natural products which were successfully synthesized in recent years (2013 to 2019). Heck …
natural products which were successfully synthesized in recent years (2013 to 2019). Heck …
Benefits of unconventional methods in the total synthesis of natural products
T Hudlicky - ACS omega, 2018 - ACS Publications
This article provides a survey of four “unconventional” methods employed in the synthesis of
natural products in the Hudlicky group. The utility of flash vacuum pyrolysis is highlighted by …
natural products in the Hudlicky group. The utility of flash vacuum pyrolysis is highlighted by …
Enantioselective Synthesis of Arene cis‐Dihydrodiols from 2‐Pyrones
XW Liang, Y Zhao, XG Si, MM Xu, JH Tan… - Angewandte …, 2019 - Wiley Online Library
An enantioselective chemical synthesis of arene cis‐dihydrodiols has been realized from 2‐
pyrones through sequential ytterbium‐catalyzed asymmetric inverse‐electron‐demand Diels …
pyrones through sequential ytterbium‐catalyzed asymmetric inverse‐electron‐demand Diels …
Enzyme Kits to facilitate the integration of biocatalysis into organic chemistry–first aid for synthetic chemists
ND Fessner, CPS Badenhorst… - ChemCatChem, 2022 - Wiley Online Library
Abstract First Aid Kits are collections of the most important medical equipment required for
quick medical assistance. Similarly, enzyme kits can provide a proficient, ready‐and easy‐to …
quick medical assistance. Similarly, enzyme kits can provide a proficient, ready‐and easy‐to …
Chemoenzymatic Total Synthesis of ent-Oxycodone: Second-, Third-, and Fourth-Generation Strategies
M Makarova, MAA Endoma-Arias… - Journal of the …, 2019 - ACS Publications
Four distinct approaches to ent-oxycodone were designed and accomplished. All rely on the
same starting material, the diene diol derived from phenethyl acetate by the whole-cell …
same starting material, the diene diol derived from phenethyl acetate by the whole-cell …
Bioinspired scalable total synthesis of opioids
X Zhou, W Li, R Zhou, X Wu, Y Huang, W Hou… - CCS …, 2021 - chinesechemsoc.org
As one of the largest and most representative families of natural medicines harvested from
plants, the mass production of opioids legitimately occupies large, worldwide farmland …
plants, the mass production of opioids legitimately occupies large, worldwide farmland …