Human pluripotent stem cell (hPSC)-derived neuron cultures have emerged as models of
electrical activity in the human brain. Microelectrode arrays (MEAs) measure changes in the …

Implanted brain–computer interfaces (iBCIs) translate brain activity recorded intracranially
into commands for virtual or physical machines to restore or rehabilitate motor, sensory or …

Intracortical microstimulation (ICMS) enables applications ranging from neuroprosthetics to
causal circuit manipulations. However, the resolution, efficacy, and chronic stability of …

The action potential is a fundamental unit of neural computation. Even though significant
advances have been made in recording large numbers of individual neurons in animal …

Brain-computer interfaces are being developed to restore movement for people living with
paralysis due to injury or disease. Although the therapeutic potential is great, long-term …

Objective. Electrical stimulation of visual cortex via a neuroprosthesis induces the perception
of dots of light ('phosphenes'), potentially allowing recognition of simple shapes even after …

Intracortical microelectrode arrays (MEAs) are used to record neural activity. However, their
implantation initiates a neuroinflammatory cascade, involving the accumulation of reactive …

Implantable neural interfaces (NIs) have emerged in the clinic as outstanding tools for the
management of a variety of neurological conditions caused by trauma or disease. However …

Objective. The Utah array is widely used in both clinical studies and neuroscience. It has a
strong track record of safety. However, it is also known that implanted electrodes promote …

Reaching and manipulating objects are crucial tasks that allow proactive interaction with our
surroundings. However, these functions are lost after neurological disorders or traumatic …