Neuroinflammatory process involved in different preclinical models of chemotherapy-induced peripheral neuropathy

G Fumagalli, L Monza, G Cavaletti, R Rigolio… - Frontiers in …, 2021 - frontiersin.org
Peripheral neuropathies are characterized by nerves damage and axonal loss, and they
could be classified in hereditary or acquired forms. Acquired peripheral neuropathies are …

The emerging antioxidant paradigm of mesenchymal stem cell therapy

R Stavely, K Nurgali - Stem Cells Translational Medicine, 2020 - academic.oup.com
Mesenchymal stem cells (multipotent stromal cells; MSCs) have been under investigation for
the treatment of diverse diseases, with many promising outcomes achieved in animal …

Pathogenesis of paclitaxel-induced peripheral neuropathy: A current review of in vitro and in vivo findings using rodent and human model systems

NP Staff, JC Fehrenbacher, M Caillaud, MI Damaj… - Experimental …, 2020 - Elsevier
Abstract Paclitaxel (Brand name Taxol) is widely used in the treatment of common cancers
like breast, ovarian and lung cancer. Although highly effective in blocking tumor progression …

Investigation of the effects of hesperidin administration on abamectin‐induced testicular toxicity in rats through oxidative stress, endoplasmic reticulum stress …

C Gur, O Kandemir, FM Kandemir - Environmental Toxicology, 2022 - Wiley Online Library
In this study, the potential effects of hesperidin (HES) on chronic toxicity caused by
abamectin (ABM) in the testicular tissue were investigated through oxidative stress …

The protective effects of hesperidin against paclitaxel-induced peripheral neuropathy in rats

HS Semis, FM Kandemir, O Kaynar, T Dogan… - Life Sciences, 2021 - Elsevier
Paclitaxel (PTX), which is widely used in the treatment of solid tumors, leads to dose
limitation because it causes peripheral neuropathy. This study was conducted to evaluate …

Function and mechanism of mesenchymal stem cells in the healing of diabetic foot wounds

X Yu, P Liu, Z Li, Z Zhang - Frontiers in Endocrinology, 2023 - frontiersin.org
Diabetes has become a global public health problem. Diabetic foot is one of the most severe
complications of diabetes, which often places a heavy economic burden on patients and …

[HTML][HTML] The effect of schwann cells/schwann cell-like cells on cell therapy for peripheral neuropathy

Q Wang, FY Chen, ZM Ling, WF Su, YY Zhao… - Frontiers in Cellular …, 2022 - frontiersin.org
Peripheral neuropathy is a common neurological issue that leads to sensory and motor
disorders. Over time, the treatment for peripheral neuropathy has primarily focused on …

Recent perspectives on the synergy of mesenchymal stem cells with micro/nano strategies in peripheral nerve regeneration-a review

M Sharifi, M Kamalabadi-Farahani, M Salehi… - … in Bioengineering and …, 2024 - frontiersin.org
Despite the intrinsic repair of peripheral nerve injury (PNI), it is important to carefully monitor
the process of peripheral nerve repair, as peripheral nerve regeneration is slow and …

Antimicrobial and antiproliferative activities of novel synthesized 6‐(quinolin‐2‐ylthio) pyridine derivatives with molecular docking study as multi‐targeted JAK2/STAT3 …

MS Nafie, S Mahgoub, AM Amer - Chemical Biology & Drug …, 2021 - Wiley Online Library
Quinoline derivatives are attracting considerable interest due to their biological importance.
In this paper, several 2‐amino‐4‐aryl‐6‐(quinolin‐2‐ylthio) pyridine‐3, 5‐dicarbonitrile …

Exosomes carried miR-181c-5p alleviates neuropathic pain in CCI rat models

YU Zhang, G Ye, J Zhao, Y Chen, L Kong… - Anais da Academia …, 2022 - SciELO Brasil
Mesenchymal stem cells (MSCs) derived exosomes (Exos) are one of the most promising
candidate for the treatment of this condition. However, the underlying molecular mechanism …