Metabolic engineering aims to develop efficient cell factories by rewiring cellular
metabolism. As one of the most commonly used cell factories, Saccharomyces cerevisiae …

Kinetic models are critical to predict the dynamic behaviour of metabolic networks.
Mechanistic kinetic models for large networks remain uncommon due to the difficulty of fitting …

A systems pharmacology model typically integrates pharmacokinetic, biochemical network,
and systems biology concepts into a unifying approach. It typically consists of a large …

The key processes in biological and chemical systems are described by networks of
chemical reactions. From molecular biology to biotechnology applications, computational …

Biological processes are often modelled using ordinary differential equations. The unknown
parameters of these models are estimated by optimizing the fit of model simulation and …

Focal drug resistant epilepsy is a neurological disorder characterized by seizures caused by
abnormal activity originating in one or more regions together called as epileptogenic zone …