Metabolism and metabolites of polychlorinated biphenyls

FA Grimm, D Hu, I Kania-Korwel… - Critical reviews in …, 2015 - Taylor & Francis
The metabolism of polychlorinated biphenyls (PCBs) is complex and has an impact on
toxicity, and thereby on the assessment of PCB risks. A large number of reactive and stable …

Endocrine disruptors from the environment affecting breast cancer

GM Calaf, R Ponce-Cusi, F Aguayo… - Oncology …, 2020 - spandidos-publications.com
Evaluation of carcinogenic substances from the environment is a challenge for scientists.
Recently, a novel approach based on 10 key characteristics of human carcinogens …

Polychlorinated biphenyls (PCBs): routes of exposure and effects on human health

DO Carpenter - Reviews on environmental health, 2006 - degruyter.com
The polychlorinated biphenyls (PCBs) are synthetic organochlorine chemicals that were
useful industrial products in the past, but their production was ended because they persist in …

Inhalation and dietary exposure to PCBs in urban and rural cohorts via congener-specific measurements

MD Ampleman, A Martinez, J DeWall… - … science & technology, 2015 - ACS Publications
Polychlorinated biphenyls (PCBs) are a group of 209 persistent organic pollutants, whose
documented carcinogenic, neurological, and respiratory toxicities are expansive and …

Mammalian models of chemically induced primary malignancies exploitable for imaging-based preclinical theragnostic research

Y Liu, T Yin, Y Feng, MM Cona… - … imaging in medicine …, 2015 - pmc.ncbi.nlm.nih.gov
Compared with transplanted tumor models or genetically engineered cancer models,
chemically induced primary malignancies in experimental animals can mimic the clinical …

Discovery of non-aroclor PCB (3, 3′-dichlorobiphenyl) in Chicago air

D Hu, A Martinez, KC Hornbuckle - Environmental science & …, 2008 - ACS Publications
Air samples were collected in Chicago, Illinois in 2007, and 3, 3′-dichlorobiphenyl (PCB11,
CAS 2050-67-1) was detected and quantified using GC/MS/MS in 91% of 184 samples. To …

Sources and toxicities of phenolic polychlorinated biphenyls (OH-PCBs)

K Dhakal, GS Gadupudi, HJ Lehmler… - … Science and Pollution …, 2018 - Springer
Polychlorinated biphenyls (PCBs), a group of 209 congeners that differ in the number and
position of chlorines on the biphenyl ring, are anthropogenic chemicals that belong to the …

Hydroxylation markedly alters how the polychlorinated biphenyl (PCB) congener, PCB52, affects gene expression in human preadipocytes

FA Gourronc, MS Chimenti, HJ Lehmler, JA Ankrum… - Toxicology in vitro, 2023 - Elsevier
Polychlorinated biphenyls (PCBs) accumulate in adipose tissue and are linked to obesity
and diabetes. The congener, PCB52 (2, 2′, 5, 5′-tetrachorobiphenyl), is found at high …

[HTML][HTML] Non‑infective occupational risk factors for hepatocellular carcinoma: A review

C Ledda, C Loreto, C Zammit… - Molecular …, 2017 - spandidos-publications.com
Liver cancer is the second leading worldwide cause of cancer‑associated mortalities.
Hepatocellular carcinoma, which accounts for the majority of liver tumors, ranks fifth among …

Polychlorinated Biphenyl (PCB) carcinogenicity with special emphasis on airborne PCBs

LW Robertson, G Ludewig - … , BIA und KRdL im VDI und DIN, 2011 - pmc.ncbi.nlm.nih.gov
Polychlorinated biphenyls (PCBs) are industrial chemicals used in various applications
requiring chemical stabilityand have now become widely dispersed. Their characteristics of …