Metal-based photosensitizers as inducers of regulated cell death mechanisms

Y Zhang, BT Doan, G Gasser - Chemical Reviews, 2023 - ACS Publications
Over the last few decades, various forms of regulated cell death (RCD) have been
discovered and were found to improve cancer treatment. Although there are several reviews …

Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy

TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

ZIF‐8 nanoparticles evoke pyroptosis for high‐efficiency cancer immunotherapy

B Ding, H Chen, J Tan, Q Meng… - Angewandte Chemie …, 2023 - Wiley Online Library
Although zeolitic imidazolate framework‐8 (ZIF‐8) has been applied in various tumor
therapies, the intrinsic immunogenicity remains unclear. Here, we initiatively discover that …

[HTML][HTML] Pyroptosis in inflammatory diseases and cancer

Z Rao, Y Zhu, P Yang, Z Chen, Y **a, C Qiao, W Liu… - Theranostics, 2022 - ncbi.nlm.nih.gov
Pyroptosis is a lytic and inflammatory type of programmed cell death that is usually triggered
by inflammasomes and executed by gasdermin proteins. The main characteristics of …

The fast-growing field of photo-driven theranostics based on aggregation-induced emission

Z Zhang, M Kang, H Tan, N Song, M Li, P **ao… - Chemical Society …, 2022 - pubs.rsc.org
Photo-driven theranostics, also known as phototheranostics, relying on the diverse excited-
state energy conversions of theranostic agents upon photoexcitation represents a significant …

Pyroptosis‐Mediated Synergistic Photodynamic and Photothermal Immunotherapy Enabled by a Tumor‐Membrane‐Targeted Photosensitive Dimer

Y Tang, HK Bisoyi, XM Chen, Z Liu, X Chen… - Advanced …, 2023 - Wiley Online Library
Overcoming the resistance to apoptosis and immunosuppression of tumor cells is a
significant challenge in augmenting the effect of cancer immunotherapy. Pyroptosis, a lytic …

Photocatalytic superoxide radical generator that induces pyroptosis in cancer cells

L Yu, Y Xu, Z Pu, H Kang, M Li… - Journal of the …, 2022 - ACS Publications
Pyroptosis, a newly characterized form of immunogenic cell death, is attracting increasing
attention as a promising approach to cancer immunotherapy. However, biocompatible …

Apoptosis-amplified assembly of porphyrin nanofiber enhances photodynamic therapy of oral tumor

X Liu, W Zhan, G Gao, Q Jiang, X Zhang… - Journal of the …, 2023 - ACS Publications
Oral squamous cell carcinoma (OSCC) is the most common oral cancer, having high
recurrence and metastasis features. In addition to surgery, photodynamic therapy (PDT) is …

Microenvironment‐responsive prodrug‐induced pyroptosis boosts cancer immunotherapy

Y **ao, T Zhang, X Ma, QC Yang, LL Yang… - Advanced …, 2021 - Wiley Online Library
The absence of tumor antigens leads to a low response rate, which represents a major
challenge in immune checkpoint blockade (ICB) therapy. Pyroptosis, which releases tumor …

Engineering of BODIPY-based theranostics for cancer therapy

Z Mao, JH Kim, J Lee, H **ong, F Zhang… - Coordination Chemistry …, 2023 - Elsevier
In recent years, BODIPY-based theranostics have increasingly been used in cancer therapy
and have achieved significant success. According to photochemical theories, the optical …