Recent advance of herbal medicines in cancer-a molecular approach

M Ali, SUD Wani, M Salahuddin, SN Manjula… - Heliyon, 2023‏ - cell.com
Bioactive compounds are crucial for an extensive range of therapeutic uses, and some
exhibit anticancer activity. Scientists advocate that phytochemicals modulate autophagy and …

Phytochemicals as chemo-preventive agents and signaling molecule modulators: current role in cancer therapeutics and inflammation

MB Ahmed, SU Islam, AAA Alghamdi… - International Journal of …, 2022‏ - mdpi.com
Cancer is one of the deadliest non communicable diseases. Numerous anticancer
medications have been developed to target the molecular pathways driving cancer …

[HTML][HTML] The potential of epigallocatechin gallate (EGCG) in targeting autophagy for cancer treatment: A narrative review

E Ferrari, S Bettuzzi, V Naponelli - International journal of molecular …, 2022‏ - mdpi.com
Autophagy is an evolutionarily conserved process for the degradation of redundant or
damaged cellular material by means of a lysosome-dependent mechanism, contributing to …

Resveratrol and neuroprotection: an insight into prospective therapeutic approaches against Alzheimer's disease from bench to bedside

F Islam, MH Nafady, MR Islam, S Saha, S Rashid… - Molecular …, 2022‏ - Springer
Alzheimer's disease (AD) is the most common cause of dementia and cognitive impairment;
yet, there is currently no treatment. A buildup of Aβ, tau protein phosphorylation, oxidative …

[HTML][HTML] Hesperidin and its aglycone hesperetin in breast cancer therapy: A review of recent developments and future prospects

KM Yap, M Sekar, YS Wu, SH Gan, NNIM Rani… - Saudi Journal of …, 2021‏ - Elsevier
Breast cancer (BC) has high incidence and mortality rates, making it a major global health
issue. BC treatment has been challenging due to the presence of drug resistance and the …

[HTML][HTML] Drug repurposing: A novel strategy to target cancer stem cells and therapeutic resistance

D Ajmeera, R Ajumeera - Genes & diseases, 2024‏ - Elsevier
Chemotherapy is an effortless and frequently used approach in cancer therapy. However, in
most cases, it can only prolong life expectancy and does not guarantee a complete cure …

p53 modulation of autophagy signaling in cancer therapies: perspectives mechanism and therapeutic targets

MA Rahman, MN Park, MDH Rahman… - Frontiers in cell and …, 2022‏ - frontiersin.org
The key tumor suppressor protein p53, additionally known as p53, represents an attractive
target for the development and management of anti-cancer therapies. p53 has been …

Molecular pharmacology and therapeutic advances of the pentacyclic triterpene lupeol

AAM Sohag, MT Hossain, MA Rahaman, P Rahman… - Phytomedicine, 2022‏ - Elsevier
Background Plant triterpenoids are major sources of nutraceuticals that provide many health
benefits to humans. Lupeol is one of the pentacyclic dietary triterpenoids commonly found in …

[HTML][HTML] Therapeutic potential of mangiferin against kidney disorders and its mechanism of action: A review

PT Lum, M Sekar, SH Gan, S Jeyabalan… - Saudi journal of …, 2022‏ - Elsevier
There is a swing in research developments concerning the utilization of natural products as
effective pharmacotherapeutic agents due to their comparatively lower toxicities than …

Recent update and drug target in molecular and pharmacological insights into autophagy modulation in cancer treatment and future progress

MA Rahman, ASM Saikat, MS Rahman, M Islam… - Cells, 2023‏ - mdpi.com
Recent evidence suggests that autophagy is a governed catabolic framework enabling the
recycling of nutrients from injured organelles and other cellular constituents via a lysosomal …