A simple yet multifaceted 90 years old, evergreen enzyme: Carbonic anhydrase, its inhibition and activation

CT Supuran - Bioorganic & Medicinal Chemistry Letters, 2023 - Elsevier
Advances in the carbonic anhydrase (CA, EC 4.2. 1.1) research over the last three decades
are presented, with an emphasis on the deciphering of the activation mechanism, the …

Coral biomineralization: From the gene to the environment

S Tambutté, M Holcomb, C Ferrier-Pagès… - Journal of Experimental …, 2011 - Elsevier
In this review we discuss the present knowledge on the biological and environmental control
of biomineralization (calcification) in hermatypic corals. We describe first the anatomy of the …

Coral calcification, cells to reefs

D Allemand, É Tambutté, D Zoccola… - Coral reefs: an ecosystem …, 2011 - Springer
In spite of more than one century and half of studies, mechanisms of coral biomineralization,
leading to coral growth and reef formation, still remain poorly known, although major global …

Carbonic anhydrase inhibitors and activators for novel therapeutic applications

CT Supuran - Future medicinal chemistry, 2011 - Taylor & Francis
Carbonic anhydrases (CAs, Enzyme Commission number 4.2. 1.1) catalyze a simple but
fundamental reaction, CO2 hydration to yield bicarbonate and protons. CAs belonging to the …

Carbonic anhydrases in anthozoan corals—A review

A Bertucci, A Moya, S Tambutté, D Allemand… - Bioorganic & medicinal …, 2013 - Elsevier
Coral reefs are among the most biologically diverse and economically important ecosystems
on the planet. The deposition of massive calcium carbonate skeletons (biomineralization or …

[HTML][HTML] Carbonic anhydrase activators for neurodegeneration: an overview

V Poggetti, S Salerno, E Baglini, E Barresi… - Molecules, 2022 - mdpi.com
Carbonic anhydrases (CAs) are a family of ubiquitous metal enzymes catalyzing the
reversible conversion of CO2 and H2O to HCO3− with the release of a proton. They play an …

Carbonic anhydrase, coral calcification and a new model of stable isotope vital effects

S Chen, AC Gagnon, JF Adkins - Geochimica et Cosmochimica Acta, 2018 - Elsevier
The stable isotope compositions of biogenic carbonates have been used for
paleoceanographic and paleoclimatic reconstructions for decades, and produced some of …

The effect of carbonic anhydrase on the kinetics and equilibrium of the oxygen isotope exchange in the CO2–H2O system: Implications for δ18O vital effects in …

J Uchikawa, RE Zeebe - Geochimica et Cosmochimica Acta, 2012 - Elsevier
Interpretations of the primary paleoceanographic information recorded in stable oxygen
isotope values (δ18O) of biogenic CaCO3 can be obscured by disequilibrium effects …

Carbonic anhydrase inhibition/activation: trip of a scientist around the world in the search of novel chemotypes and drug targets

CT Supuran - Current Pharmaceutical Design, 2010 - ingentaconnect.com
Carbonic anhydrases (CAs, EC 4.2. 1.1) are metalloenzymes which catalyze CO2 hydration
to bicarbonate and protons. Five genetically distinct classes are known, which represent an …

A New Coral Carbonic Anhydrase in Stylophora pistillata

A Bertucci, S Tambutté, CT Supuran, D Allemand… - Marine …, 2011 - Springer
Scleractinian corals are of particular interest due to their ability to establish an intracellular
mutualistic symbiosis with phototrophic dinoflagellates and to deposit high rates of calcium …