Clinicians have been interested in the macroscopic and protocol (fig 1), based on that
described by Pin et al7 using a relatively low output ultrasonic nebuliser (output 0.9 …

Objective To review the fast-develo** topic of assessment of exhaled breath components
to improve the diagnosis and monitoring of respiratory and systemic diseases. Data Sources …

Asthma and chronic obstructive pulmonary disease are characterized by chronic airway
inflammation. Studies using bronchoalveolar lavage (BAL) have shown an increased …

Induced sputum cell counts provide a relatively noninvasive method to evaluate the
presence, type, and degree of inflammation in the airways of the lungs. Their interpretation …

The Belgian severe asthma registry is a web-based registry encompassing demographic,
clinical, functional and inflammatory data of severe asthmatics (SA), aiming at improving …

Although airway inflammation is recognized as a key feature of asthma, the characteristics of
airway inflammation in children with acute severe asthma are not well defined. The aim of …

Background: Airway eosinophilic inflammation is a characteristic feature of asthma. This can
be assessed directly by measurement of eosinophils and eosinophilic cationic protein (ECP) …

Sputum induction has recently been proposed as the only direct noninvasive method for
measuring airway inflammatory indices. The reference values and the distribution of cells in …

We have investigated the time-course of symptoms, forced expiratory volume in one second
(FEV1), and the airway inflammatory changes in sputum selected from saliva and blood of …

Human tracheobronchial epithelial cells grown in air-liquid interface culture have emerged
as a powerful tool for the study of airway biology. In this study, we have investigated whether …