The role of diffusion tensor imaging in the diagnosis, prognosis, and assessment of recovery and treatment of spinal cord injury: a systematic review

OA Zaninovich, MJ Avila, M Kay, JL Becker… - Neurosurgical …, 2019 - thejns.org
OBJECTIVE Diffusion tensor imaging (DTI) is an MRI tool that provides an objective,
noninvasive, in vivo assessment of spinal cord injury (SCI). DTI is significantly better at …

Diffusion MRI quantifies early axonal loss in the presence of nerve swelling

TH Lin, CW Chiang, CJ Perez-Torres, P Sun… - Journal of …, 2017 - Springer
Background Magnetic resonance imaging markers have been widely used to detect and
quantify white matter pathologies in multiple sclerosis. We have recently developed a …

MRI-based assessment of function and dysfunction in myelinated axons

WM Spees, TH Lin, P Sun, C Song… - Proceedings of the …, 2018 - National Acad Sciences
Repetitive electrical activity produces microstructural alteration in myelinated axons, which
may afford the opportunity to noninvasively monitor function of myelinated fibers in …

Imaging of spontaneous ventriculomegaly and vascular malformations in Wistar rats: implications for preclinical research

TW Tu, LC Turtzo, RA Williams… - … of Neuropathology & …, 2014 - academic.oup.com
Wistar rats are widely used in biomedical research and commonly serve as a model
organism in neuroscience studies. In most cases when noninvasive imaging is not used …

Non-local means based Rician noise filtering for diffusion tensor and kurtosis imaging in human brain and spinal cord

Z Zhang, D Vernekar, W Qian, M Kim - BMC Medical Imaging, 2021 - Springer
Background To investigate the effect of using a Rician nonlocal means (NLM) filter on
quantification of diffusion tensor (DT)-and diffusion kurtosis (DK)-derived metrics in various …

Diffusion basis spectrum imaging measures anti-inflammatory and neuroprotective effects of fingolimod on murine optic neuritis

R Yang, TH Lin, J Zhan, S Lai, C Song, P Sun, Z Ye… - NeuroImage: Clinical, 2021 - Elsevier
Objective To prospectively determine whether diffusion basis spectrum imaging (DBSI)
detects, differentiates and quantitates coexisting inflammation, demyelination, axonal injury …

Super-resolution diffusion tensor imaging for delineating the facial nerve in patients with vestibular schwannoma

L Epprecht, ED Kozin, M Piccirelli… - … Surgery Part B: Skull …, 2019 - thieme-connect.com
Objectives Predicting the course of cranial nerves (CNs) VII and VIII in the cerebellopontine
angle on preoperative imaging for vestibular schwannoma (VS) may help guide surgical …

Comparison of Diffusion MRI Acquisition Protocols for the In Vivo Characterization of the Mouse Spinal Cord: Variability Analysis and Application to an Amyotrophic …

M Figini, A Scotti, S Marcuzzo, S Bonanno, F Padelli… - Plos one, 2016 - journals.plos.org
Diffusion-weighted Magnetic Resonance Imaging (dMRI) has relevant applications in the
microstructural characterization of the spinal cord, especially in neurodegenerative …

Diffusion MRI differentiated acute inflammation from axonal injury but missed axonal loss

THA Lin, M Wallendorf, P Sun… - Proc Intl Soc Mag Reson …, 2017 - archive.ismrm.org
Diffusion MRI with higher b-values and custom-designed diffusion schemes are critical to
identify subtle and coexisting pathology in CNS. In the current study, we employed single …

Diffusion MRI Quantifies Hippocampal CA1 Dendritic Loss and Inflammation in TMEV-Induced Epilepsy

J Zhan, TH Lin, JE Libbey, P Sun, ZZ Ye, C Song… - archive.ismrm.org
Hippocampal neuronal damage and inflammation are the hallmark pathologies of epilepsy.
We demonstrate the capability of diffusion based spectrum imaging (DBSI) to quantify …