Remyelination in multiple sclerosis: from basic science to clinical translation
The treatment of multiple sclerosis has been transformed by the successful development of
immunotherapies that efficiently reduce disease activity and related clinical relapses during …
immunotherapies that efficiently reduce disease activity and related clinical relapses during …
[HTML][HTML] Myelin in the central nervous system: structure, function, and pathology
C Stadelmann, S Timmler… - Physiological …, 2019 - journals.physiology.org
Oligodendrocytes generate multiple layers of myelin membrane around axons of the central
nervous system to enable fast and efficient nerve conduction. Until recently, saltatory nerve …
nervous system to enable fast and efficient nerve conduction. Until recently, saltatory nerve …
Oligodendroglia: metabolic supporters of neurons
Oligodendrocytes are glial cells that populate the entire CNS after they have differentiated
from oligodendrocyte progenitor cells. From birth onward, oligodendrocytes initiate wrap** …
from oligodendrocyte progenitor cells. From birth onward, oligodendrocytes initiate wrap** …
Functionally distinct subgroups of oligodendrocyte precursor cells integrate neural activity and execute myelin formation
R Marisca, T Hoche, E Agirre, LJ Hoodless… - Nature …, 2020 - nature.com
Recent reports have revealed that oligodendrocyte precursor cells (OPCs) are
heterogeneous. It remains unclear whether such heterogeneity reflects different subtypes of …
heterogeneous. It remains unclear whether such heterogeneity reflects different subtypes of …
Molecular control of oligodendrocyte development
Myelin is a multilayer lipid membrane structure that wraps and insulates axons, allowing for
the efficient propagation of action potentials. During developmental myelination of the …
the efficient propagation of action potentials. During developmental myelination of the …