Acute symptomatic seizures secondary to autoimmune encephalitis and autoimmune‐associated epilepsy: conceptual definitions

C Steriade, J Britton, RC Dale, A Gadoth, SR Irani… - …, 2020 - Wiley Online Library
Seizures are a well‐recognized and often prominent manifestation of autoimmune
encephalitic syndromes. Progress in detection of pathogenic neural autoantibodies has led …

Autoimmune seizures and epilepsy

C Geis, J Planagumà, M Carreño… - The Journal of …, 2019 - Am Soc Clin Investig
The rapid expansion in the number of encephalitis disorders associated with autoantibodies
against neuronal proteins has led to an incremental increase in use of the term “autoimmune …

Impact of predictive, preventive and precision medicine strategies in epilepsy

R Nabbout, M Kuchenbuch - Nature Reviews Neurology, 2020 - nature.com
Over the last decade, advances in genetics, neuroimaging and EEG have enabled the
aetiology of epilepsy to be identified earlier in the disease course than ever before. At the …

LGI1 antibody encephalitis: acute treatment comparisons and outcome

A Rodriguez, CJ Klein, E Sechi, E Alden… - Journal of Neurology …, 2022 - jnnp.bmj.com
Objective To compare acute treatment responses and long-term outcome in leucine-rich
glioma-inactivated 1 (LGI1) antibody encephalitis. Methods Retrospective case series of 118 …

Prognosticating autoimmune encephalitis: a systematic review

J Broadley, U Seneviratne, P Beech, K Buzzard… - Journal of …, 2019 - Elsevier
Objective To perform a systematic review of the current scientific literature in order to identify
variables associated with patient prognosis in autoimmune encephalitis. Methods We …

Neurological autoantibody prevalence in epilepsy of unknown etiology

D Dubey, A Alqallaf, R Hays, M Freeman… - JAMA …, 2017 - jamanetwork.com
Importance Autoimmune epilepsy is an underrecognized condition, and its true incidence is
unknown. Identifying patients with an underlying autoimmune origin is critical because these …

Randomized placebo‐controlled trial of intravenous immunoglobulin in autoimmune LGI1/CASPR2 epilepsy

D Dubey, J Britton, A McKeon, A Gadoth… - Annals of …, 2020 - Wiley Online Library
Objective Drug‐resistant seizures are common in patients with leucine‐rich, glioma‐
inactivated 1 (LGI1)‐IgG associated and contactin‐associated protein‐like 2 (CASPR2)‐IgG …

Seizures and risk of epilepsy in autoimmune and other inflammatory encephalitis

M Spatola, J Dalmau - Current opinion in neurology, 2017 - journals.lww.com
Although seizures are frequent in all types of autoimmune encephalitis, the risk for chronic
epilepsy is dependent on the antigen: lower if located on the cell-surface, and higher if …

[HTML][HTML] Autoimmune epilepsy

KS Husari, D Dubey - Neurotherapeutics, 2019 - Elsevier
The field of autoimmune epilepsy has evolved substantially in the last few decades with
discovery of several neural autoantibodies and improved mechanistic understanding of …

Predictive models in the diagnosis and treatment of autoimmune epilepsy

D Dubey, J Singh, JW Britton, SJ Pittock… - …, 2017 - Wiley Online Library
Objective To validate predictive models for neural antibody positivity and immunotherapy
response in epilepsy. Methods We conducted a retrospective study of epilepsy cases at …