Synergistic antibacterial strategy based on photodynamic therapy: Progress and perspectives

X Hu, H Zhang, Y Wang, BC Shiu, JH Lin… - Chemical Engineering …, 2022 - Elsevier
The dramatic increase in drug resistant bacteria resistance to existing conventional
antibiotics poses a great challenge to the effective treatment of infectious diseases …

Singlet molecular oxygen reactions with nucleic acids, lipids, and proteins

P Di Mascio, GR Martinez, S Miyamoto… - Chemical …, 2019 - ACS Publications
Singlet oxygen (1O2) is a biologically relevant reactive oxygen species capable of efficiently
reacting with cellular constituents. The resulting oxidatively generated damage to nucleic …

Antimicrobial photodynamic inactivation: a bright new technique to kill resistant microbes

MR Hamblin - Current opinion in microbiology, 2016 - Elsevier
Highlights•PDT uses light-activated photosensitizers to produce reactive oxygen species
that kill microbial cells.•Polycationic chlorin (e6) conjugates, stable synthetic bacteriochlorins …

Photodynamic therapy: a new antimicrobial approach to infectious disease?

MR Hamblin, T Hasan - Photochemical & Photobiological Sciences, 2004 - pubs.rsc.org
Photodynamic therapy (PDT) employs a non-toxic dye, termed a photosensitizer (PS), and
low intensity visible light which, in the presence of oxygen, combine to produce cytotoxic …

Antimicrobial strategies centered around reactive oxygen species–bactericidal antibiotics, photodynamic therapy, and beyond

F Vatansever, WCMA de Melo, P Avci… - FEMS microbiology …, 2013 - academic.oup.com
Reactive oxygen species (ROS) can attack a diverse range of targets to exert antimicrobial
activity, which accounts for their versatility in mediating host defense against a broad range …

Rejuvenated photodynamic therapy for bacterial infections

Q Jia, Q Song, P Li, W Huang - Advanced healthcare materials, 2019 - Wiley Online Library
The emergence of multidrug resistant bacterial strains has hastened the exploration of
advanced microbicides and antibacterial techniques. Photodynamic antibacterial therapy …

Nanotechnology-based drug delivery systems for photodynamic therapy of cancer: a review

GMF Calixto, J Bernegossi, LM De Freitas, CR Fontana… - Molecules, 2016 - mdpi.com
Photodynamic therapy (PDT) is a promising alternative approach for improved cancer
treatment. In PDT, a photosensitizer (PS) is administered that can be activated by light of a …

Nanomedicine and advanced technologies for burns: Preventing infection and facilitating wound healing

MAM Jahromi, PS Zangabad, SMM Basri… - Advanced drug delivery …, 2018 - Elsevier
According to the latest report from the World Health Organization, an estimated 265,000
deaths still occur every year as a direct result of burn injuries. A widespread range of these …

[HTML][HTML] Curcumin as a photosensitizer: From molecular structure to recent advances in antimicrobial photodynamic therapy

LD Dias, KC Blanco, IS Mfouo-Tynga, NM Inada… - … of Photochemistry and …, 2020 - Elsevier
Nowadays multi-drug resistant microorganisms is a serious public health problem
worldwide. To overcome it, new antimicrobial strategies have been developed. Among them …

Photosensitization and controlled photosensitization with BODIPY dyes

A Turksoy, D Yildiz, EU Akkaya - Coordination Chemistry Reviews, 2019 - Elsevier
Highly versatile BODIPY dyes proved themselves to be very useful as photosensitizers.
These dyes can be derivatized to absorb essentially anywhere in the visible the near IR …