Patients with a diverse spectrum of rare genetic disorders can present with inflammatory
bowel disease (monogenic IBD). Patients with these disorders often develop symptoms …

In this review, we provide an update on genome-wide association studies (GWAS) in
inflammatory bowel disease (IBD). In addition, we summarize progress in defining the …

Background Crohn's disease and ulcerative colitis are complex disorders with some shared
and many unique predisposing genes. Accurate phenotype classification is essential in …

Fistulating Crohn's disease (CD) comprises fistulae arising in the perianal area, together
with those communicating between the intestine and other organs or the abdominal wall …

Very early onset inflammatory bowel disease (VEO-IBD) is defined as IBD presenting before
6 years of age. When compared with IBD diagnosed in older children, VEO-IBD has some …

Background & aims Monogenic forms of inflammatory bowel disease (IBD) illustrate the
essential roles of individual genes in pathways and networks safeguarding immune …

Background & Aims The Paris pediatric modification of the Montreal classification defines
very early onset inflammatory bowel disease (VEO-IBD) as a form of IBD distinct from that of …

Gastrointestinal disorders such as chronic or acute diarrhea, malabsorption, abdominal
pain, and inflammatory bowel diseases can indicate immune deficiency. The gastrointestinal …

The rate of pediatric inflammatory bowel disease (IBD) has been increasing over the last
decade and this increase has occurred most rapidly in the youngest children diagnosed< 6 …

Inflammatory bowel disease (IBD) includes a spectrum of diseases from ulcerative colitis
(UC) to Crohn's disease (CD). Many studies have addressed the changes in the microbiota …