Handedness in Alzheimer's disease: A systematic review

Y Abuduaini, W Chen, XZ Kong - Brain Research, 2024 - Elsevier
Handedness has traditionally been employed as a proxy of brain lateralization in research.
Alzheimer's disease (AD) manifests as a neurodegenerative disorder characterized by …

Microstructural asymmetry in the human cortex

B Wan, A Saberi, C Paquola, HL Schaare… - Nature …, 2024 - nature.com
The human cerebral cortex shows hemispheric asymmetry, yet the microstructural basis of
this asymmetry remains incompletely understood. Here, we probe layer-specific …

[HTML][HTML] The Balance in the Head: How Developmental Factors Explain Relationships Between Brain Asymmetries and Mental Diseases

M Manns, G Juckel, N Freund - Brain Sciences, 2025 - mdpi.com
Cerebral lateralisation is a core organising principle of the brain that is characterised by a
complex pattern of hemispheric specialisations and interhemispheric interactions. In various …

[HTML][HTML] Distinct longitudinal brain white matter microstructure changes and associated polygenic risk of common psychiatric disorders and Alzheimer's disease in the …

M Korbmacher, D van der Meer, D Beck… - … Psychiatry Global Open …, 2024 - Elsevier
Background During the course of adulthood and aging, white matter (WM) structure and
organization are characterized by slow degradation processes such as demyelination and …

[HTML][HTML] Deep learning enables accurate brain tissue microstructure analysis based on clinically feasible diffusion magnetic resonance imaging

Y Li, Z Zhuo, C Liu, Y Duan, Y Shi, T Wang, R Li… - NeuroImage, 2024 - Elsevier
Diffusion magnetic resonance imaging (dMRI) allows non-invasive assessment of brain
tissue microstructure. Current model-based tissue microstructure reconstruction techniques …

[PDF][PDF] Freesurfer version-shuffling can enhance brain age predictions

M Korbmacher, LT Westlye, I Maximov - 2024 - hvlopen.brage.unit.no
Key points• FreeSurfer version-dependent variability on brain age predictions is on average
small when varying training-test splits.• FreeSurfer version differences can introduce …

Global brain asymmetry and its variations in aging and related diseases

H Hu, Y Pu, Y Abuduaini, X Wang, C Francks… - bioRxiv, 2024 - biorxiv.org
Functional lateralization is a cardinal feature of human brain, and deviations from typical
lateralization are observed in various brain disorders. Although this phenomenon has been …

Multimodal predictors of functional and cognitive decline in relapsing-remitting multiple sclerosis

M Korbmacher, IA Lie, K Wesnes, E Westman… - medRxiv, 2025 - medrxiv.org
The underlying mechanisms for neurodegeneration in multiple sclerosis are complex and
incompletely understood. Multivariate and multimodal investigations integrating …

An estimate of the longitudinal pace of aging from a single brain scan predicts dementia conversion, morbidity, and mortality

ET Whitman, ML Elliott, AR Knodt, WC Abraham… - …, 2024 - pmc.ncbi.nlm.nih.gov
To understand how aging affects functional decline and increases disease risk, it is
necessary to develop accurate and reliable measures of how fast a person is aging …

Cross-sectional brain age assessments are limited in predicting future brain change

M Korbmacher, D Vidal-Pineiro, MY Wang… - bioRxiv, 2024 - biorxiv.org
The concept of brain age (BA) describes an integrative imaging marker of brain health, often
suggested to reflect ageing processes. However, the degree to which cross-sectional MRI …