A comprehensive analysis and anti-cancer activities of quercetin in ROS-mediated cancer and cancer stem cells
Reactive oxygen species (ROS) induce carcinogenesis by causing genetic mutations,
activating oncogenes, and increasing oxidative stress, all of which affect cell proliferation …
activating oncogenes, and increasing oxidative stress, all of which affect cell proliferation …
[HTML][HTML] Advanced implications of nanotechnology in disease control and environmental perspectives
Nanotechnology encompasses a wide range of devices derived from biology, engineering,
chemistry, and physics, and this scientific field is composed of great collaboration among …
chemistry, and physics, and this scientific field is composed of great collaboration among …
Natural flavonoids effectively block the CD81 receptor of hepatocytes and inhibit HCV infection: A computational drug development approach
Hepatitis C virus (HCV) infection is a major public health concern, and almost two million
people are infected per year globally. This is occurred by the diverse spectrum of viral …
people are infected per year globally. This is occurred by the diverse spectrum of viral …
Assessment of quercetin antiemetic properties: In vivo and in silico investigations on receptor binding affinity and synergistic effects
Quercetin (QUA), a flavonoid compound, is ubiquitously found in plants and has
demonstrated a diverse range of biological activities. The primary objective of the current …
demonstrated a diverse range of biological activities. The primary objective of the current …
Computational investigation of natural compounds as potential main protease (Mpro) inhibitors for SARS-CoV-2 virus
Abstract The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) is significantly impacting human lives …
respiratory syndrome coronavirus 2 (SARS-CoV-2) is significantly impacting human lives …
Study of MDM2 as Prognostic Biomarker in Brain-LGG Cancer and Bioactive Phytochemicals Inhibit the p53-MDM2 Pathway: A Computational Drug Development …
An evaluation of the expression and predictive significance of the MDM2 gene in brain lower-
grade glioma (LGG) cancer was carried out using onco-informatics pipelines. Several …
grade glioma (LGG) cancer was carried out using onco-informatics pipelines. Several …
Molecular Dynamics Simulation and Pharmacoinformatic Integrated Analysis of Bioactive Phytochemicals from Azadirachta indica (Neem) to Treat Diabetes Mellitus
Diabetes mellitus is a chronic hormonal and metabolic disorder in which our body cannot
generate necessary insulin or does not act in response to it, accordingly, ensuing in …
generate necessary insulin or does not act in response to it, accordingly, ensuing in …
Neuroprotective potential of biflavone ginkgetin: a review
Neurological disorders are becoming more common, and there is an intense search for
molecules that can help treat them. Several natural components, especially those from the …
molecules that can help treat them. Several natural components, especially those from the …
Colloidal aggregation confounds cell-based Covid-19 antiviral screens
Colloidal aggregation is one of the largest contributors to false positives in early drug
discovery. Here, we consider aggregation's role in cell-based infectivity assays in Covid-19 …
discovery. Here, we consider aggregation's role in cell-based infectivity assays in Covid-19 …
Gigantol, a promising natural drug for inflammation: a literature review and computational based study
Gigantol, a bibenzyl compound extracted from various medicinal plants, has shown a
number of biological activities, making it an attractive candidate for potential medical …
number of biological activities, making it an attractive candidate for potential medical …