The identification and detection of disease-related biomarkers is essential for early clinical
diagnosis, evaluating disease progression, and for the development of therapeutics …

For cognitive processes to function well, it is essential that the brain is optimally supplied
with oxygen and blood. In recent years, evidence has emerged suggesting that cerebral …

Functional near-infrared spectroscopy (fNIRS) is a noninvasive neuroimaging technique that
uses low-levels of light (650–900 nm) to measure changes in cerebral blood volume and …

This year marks the 20th anniversary of functional near-infrared spectroscopy and imaging
(fNIRS/fNIRI). As the vast majority of commercial instruments developed until now are based …

This review is aimed at celebrating the upcoming 20th anniversary of the birth of human
functional near-infrared spectroscopy (fNIRS). After the discovery in 1992 that the functional …

Oxygen saturation in the arterial blood (SaO2) provides information on the adequacy of
respiratory function. SaO2 can be assessed noninvasively by pulse oximetry, which is based …

Safe locomotion is a crucial aspect of human daily living that requires well-functioning motor
control processes. The human neuromotor control of daily activities such as walking relies …

Tumor hypoxia is a well-established biological phenomenon that affects the curability of
solid tumors, regardless of treatment modality. Especially for head and neck cancer patients …

Diffuse correlation spectroscopy (DCS) uses the temporal fluctuations of near-infrared (NIR)
light to measure cerebral blood flow (CBF) non-invasively. Here, we provide a brief history of …

This review describes the diffusion model for light transport in tissues and the medical
applications of diffuse light. Diffuse optics is particularly useful for measurement of tissue …