Self-healing injectable hydrogels for tissue regeneration

P Bertsch, M Diba, DJ Mooney… - Chemical …, 2022‏ - ACS Publications
Biomaterials with the ability to self-heal and recover their structural integrity offer many
advantages for applications in biomedicine. The past decade has witnessed the rapid …

Neuroinflammatory mechanisms of blood-brain barrier damage in ischemic stroke

C Yang, KE Hawkins, S Doré… - American Journal of …, 2019‏ - journals.physiology.org
As part of the neurovascular unit, the blood-brain barrier (BBB) is a unique, dynamic
regulatory boundary that limits and regulates the exchange of molecules, ions, and cells …

Regenerative therapies for central nervous system diseases: a biomaterials approach

RY Tam, T Fuehrmann, N Mitrousis… - …, 2014‏ - nature.com
The central nervous system (CNS) has a limited capacity to spontaneously regenerate
following traumatic injury or disease, requiring innovative strategies to promote tissue and …

Optimization of thermoresponsive chitosan/β-glycerophosphate hydrogels for injectable neural tissue engineering application

MH Bhuiyan, AN Clarkson, MA Ali - Colloids and Surfaces B: Biointerfaces, 2023‏ - Elsevier
Regeneration of neural tissue and recovery of lost functions following an accident or disease
to the central nervous system remains a major challenge worldwide, with limited treatment …

Design of injectable materials to improve stem cell transplantation

LM Marquardt, SC Heilshorn - Current stem cell reports, 2016‏ - Springer
Stem cell-based therapies are steadily gaining traction for regenerative medicine
approaches to treating disease and injury throughout the body. While a significant body of …

Concentration-dependent rheological properties of ECM hydrogel for intracerebral delivery to a stroke cavity

AR Massensini, H Ghuman, LT Saldin, CJ Medberry… - Acta biomaterialia, 2015‏ - Elsevier
Biomaterials composed of mammalian extracellular matrix (ECM) promote constructive
tissue remodeling with minimal scar tissue formation in many anatomical sites. However, the …

Advances of nano drug delivery system for the theranostics of ischemic stroke

W Lv, Y Liu, S Li, L Lv, H Lu, H **n - Journal of nanobiotechnology, 2022‏ - Springer
From the global perspective, stroke refers to a highly common cause of disability and death.
Ischemic stroke (IS), attributed to blood vessel blockage, preventing the flow of blood to …

Advancements in regenerative hydrogels in skin wound treatment: A comprehensive review

G Olteanu, SM Neacșu, FA Joița, AM Musuc… - International Journal of …, 2024‏ - mdpi.com
This state-of-the-art review explores the emerging field of regenerative hydrogels and their
profound impact on the treatment of skin wounds. Regenerative hydrogels, composed …

Defining and designing polymers and hydrogels for neural tissue engineering

ER Aurand, KJ Lampe, KB Bjugstad - Neuroscience research, 2012‏ - Elsevier
The use of biomaterials, such as hydrogels, as neural cell delivery devices is becoming
more common in areas of research such as stroke, traumatic brain injury, and spinal cord …

[HTML][HTML] Hydrogel-assisted neuroregeneration approaches towards brain injury therapy: A state-of-the-art review

VA Kornev, EA Grebenik, AB Solovieva… - Computational and …, 2018‏ - Elsevier
Recent years have witnessed the development of an enormous variety of hydrogel-based
systems for neuroregeneration. Formed from hydrophilic polymers and comprised of up to …