Nuclear magnetic resonance (NMR) is the spectroscopic technique of choice for determining
molecular conformations in solution at atomic resolution. As solution NMR spectra are rich in …

The effect of peptide-to-peptoid substitutions on the passive membrane permeability of an N-
methylated cyclic hexapeptide is examined. In general, substitutions maintained …

Solving conformations of cyclic peptides can provide insight into structure–activity and
structure–property relationships, which can help in the design of compounds with improved …

MSpin‐JCoupling is a modular program for the prediction of scalar couplings using a large
variety of Karplus relationships. The program was specially designed for small molecule …

The Solution Structure of (+)-Spongistatin 1 in DMSO | Organic Letters Recently Viewedclose
modal ACS ACS Publications C&EN CAS Find my institution Log In ACS Publications. Most …

Albert W. Overhauser, while holding a postdoctoral position at the Department of Physics of
the University of Illinois at Urbana (IL), theoretically proposed in 1953 that if the electron spin …

NMR spectroscopy is one of the most powerful methods to explore the structure and
dynamics of peptides in solution. The three-dimensional solution structures of peptides, and …

Proazaphosphatranes are intriguing ligand architectures comprising a bicyclic cage of
flexible nature. They can undergo structural deformations due to transannulation while …

Despite the prevalence of head-to-side chain threonine linkages in natural products, their
incorporation has been underexplored in synthetic cyclic peptides. Herein we investigate a …

Indirect and unsymmetrical indirect covariance NMR provide powerful tools to compute and
visualize correlation information by transforming component spectra into combined spectral …