Making waves: how ultrasound-targeted drug delivery is changing pharmaceutical approaches
Administration of drugs through oral and intravenous routes is a mainstay of modern
medicine, but this approach suffers from limitations associated with off-target side effects and …
medicine, but this approach suffers from limitations associated with off-target side effects and …
Inducible endothelial leakiness in nanotherapeutic applications
All intravenous delivered nanomedicine needs to escape from the blood vessel to exert their
therapeutic efficacy at their designated site of action. Failure to do so increases the …
therapeutic efficacy at their designated site of action. Failure to do so increases the …
Physical triggering strategies for drug delivery
Physically triggered systems hold promise for improving drug delivery by enhancing the
controllability of drug accumulation and release, lowering non-specific toxicity, and …
controllability of drug accumulation and release, lowering non-specific toxicity, and …
Recent progress in lipid nanoparticles for cancer theranostics: opportunity and challenges
Cancer is one of the major leading causes of mortality in the world. The implication of
nanotherapeutics in cancer has garnered splendid attention owing to their capability to …
nanotherapeutics in cancer has garnered splendid attention owing to their capability to …
Ultrasound-responsive nanocarriers for breast cancer chemotherapy
Breast cancer is the most common type of cancer and it is treated with surgical intervention,
radiotherapy, chemotherapy, or a combination of these regimens. Despite chemotherapy's …
radiotherapy, chemotherapy, or a combination of these regimens. Despite chemotherapy's …
State-of-the-art of ultrasound-triggered drug delivery from ultrasound-responsive drug carriers
Introduction Delivering sufficient therapeutics at the target site without off-target effects is a
major goal of drug delivery technology innovation. Among the established methods …
major goal of drug delivery technology innovation. Among the established methods …
[HTML][HTML] Effect of acoustic cluster therapy (ACT®) combined with chemotherapy in a patient-derived xenograft mouse model of pancreatic cancer
S Ng, AJ Healey, PC Sontum, S Kvåle, SH Torp… - Journal of Controlled …, 2022 - Elsevier
Pancreatic ductal adenocarcinomas respond poorly to chemotherapy, in part due to the
dense tumor stroma that hinders drug delivery. Ultrasound (US) in combination with …
dense tumor stroma that hinders drug delivery. Ultrasound (US) in combination with …
Enhancing Targeted Therapy in Breast Cancer by Ultrasound-Responsive Nanocarriers
Currently, the response to cancer treatments is highly variable, and severe side effects and
toxicity are experienced by patients receiving high doses of chemotherapy, such as those …
toxicity are experienced by patients receiving high doses of chemotherapy, such as those …
Acoustic nanodrops for biomedical applications
Acoustic nanodrops are designed to vaporize into ultrasound-responsive microbubbles,
which present certain challenges nonexistent for conventional nanoemulsions. The …
which present certain challenges nonexistent for conventional nanoemulsions. The …
[HTML][HTML] Magnetic mediators for ultrasound theranostics
The theranostics paradigm is based on the concept of combining therapeutic and diagnostic
modalities into one platform to improve the effectiveness of treatment. Combinations of …
modalities into one platform to improve the effectiveness of treatment. Combinations of …