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Meta-analysis of chromosomal aberrations as a biomarker of exposure in healthcare workers occupationally exposed to antineoplastic drugs
C Roussel, KL Witt, PB Shaw, TH Connor - Mutation Research/Reviews in …, 2019 - Elsevier
Many antineoplastic drugs used to treat cancer, particularly alkylating agents and
topoisomerase inhibitors, are known to induce genetic damage in patients. Elevated levels …
topoisomerase inhibitors, are known to induce genetic damage in patients. Elevated levels …
Occupational exposure to cytostatic/antineoplastic drugs and cytogenetic damage measured using the lymphocyte cytokinesis-block micronucleus assay: A systematic …
M Villarini, V Gianfredi, S Levorato, S Vannini… - … Research/Reviews In …, 2016 - Elsevier
Many studies have reported the occurrence of work-environment contamination by
antineoplastic drugs (ANPD), with significant incorporation of trace amounts of these …
antineoplastic drugs (ANPD), with significant incorporation of trace amounts of these …
Closed‐system drug‐transfer devices plus safe handling of hazardous drugs versus safe handling alone for reducing exposure to infusional hazardous drugs in …
Background Occupational exposure to hazardous drugs can decrease fertility and result in
miscarriages, stillbirths, and cancers in healthcare staff. Several recommended practices …
miscarriages, stillbirths, and cancers in healthcare staff. Several recommended practices …
Structural chromosomal aberrations as potential risk markers in incident cancer patients
S Vodenkova, Z Polivkova, L Musak… - …, 2015 - academic.oup.com
Epidemiological prospective studies have shown that increased chromosomal aberrations
(CAs) in peripheral blood lymphocytes may predict cancer risk. Here, we report CAs in newly …
(CAs) in peripheral blood lymphocytes may predict cancer risk. Here, we report CAs in newly …
Occupational exposure to cytotoxic drugs: the importance of surface cleaning to prevent or minimise exposure
Sažetak Healthcare workers who prepare or administer cytotoxic agents run the risk of
exposure, and the risks for health are real even at doses lower than those applied in cancer …
exposure, and the risks for health are real even at doses lower than those applied in cancer …
[HTML][HTML] The handling of hazardous medications by nurses and midwives: A retrospective cohort study
Background Occupational exposure of healthcare workers to hazardous medications can be
potentially harmful. Hazardous medications can be carcinogenic, developmentally toxic …
potentially harmful. Hazardous medications can be carcinogenic, developmentally toxic …
[HTML][HTML] The oxidative stress parameters as useful tools in evaluating the DNA damage and changes in the complete blood count in hospital workers exposed to low …
Hospital workers at the Oncology Department are occupationally exposed to antineoplastic
drugs (ANTNP) or low doses of ionizing radiation (Irrad). Therefore, the aim of this study was …
drugs (ANTNP) or low doses of ionizing radiation (Irrad). Therefore, the aim of this study was …
Environmental and biological monitoring on an oncology ward during a complete working week
M Koller, A Böhlandt, C Haberl, D Nowak, R Schierl - Toxicology letters, 2018 - Elsevier
Workplace exposure to antineoplastic drugs (AD) is still of evident concern to all
occupationally exposed persons in the healthcare sector as residues in relevant …
occupationally exposed persons in the healthcare sector as residues in relevant …
[HTML][HTML] The male reproductive toxicity after 5-Fluorouracil exposure: DNA damage, oxidative stress, and mitochondrial dysfunction in vitro and in vivo
W Yuan, G Ji, X Shi, Z Sun, C Liu, Y Yu, W Li… - Ecotoxicology and …, 2024 - Elsevier
Fluorouracil (5-FU), a chemotherapeutic drug used to treat a variety of cancers, can enter the
environment through different routes, causing serious public health and environmental …
environment through different routes, causing serious public health and environmental …
Genotoxic evaluation of occupational exposure to antineoplastic drugs
During the last years, several reports have provided evidence about adverse health effects
on personal involved in Antineoplastic Drugs (ANPD) handling. ANPD has the ability to bind …
on personal involved in Antineoplastic Drugs (ANPD) handling. ANPD has the ability to bind …