Single-molecule localization microscopy in eukaryotes

M Sauer, M Heilemann - Chemical reviews, 2017 - ACS Publications
Super-resolution fluorescence imaging by photoactivation or photoswitching of single
fluorophores and position determination (single-molecule localization microscopy, SMLM) …

Super-resolution microscopy: from single molecules to supramolecular assemblies

AM Sydor, KJ Czymmek, EM Puchner, V Mennella - Trends in cell biology, 2015 - cell.com
Super-resolution microscopy (SRM) methods have allowed scientists to exceed the
diffraction limit of light, enabling the discovery and investigation of cellular structures at the …

Super-resolution microscopy with DNA-PAINT

J Schnitzbauer, MT Strauss, T Schlichthaerle… - Nature protocols, 2017 - nature.com
Super-resolution techniques have begun to transform biological and biomedical research by
allowing researchers to observe structures well below the classic diffraction limit of light …

Motion of VAPB molecules reveals ER–mitochondria contact site subdomains

CJ Obara, J Nixon-Abell, AS Moore, F Riccio… - Nature, 2024 - nature.com
To coordinate cellular physiology, eukaryotic cells rely on the rapid exchange of molecules
at specialized organelle–organelle contact sites,. Endoplasmic reticulum–mitochondrial …

Force loading explains spatial sensing of ligands by cells

R Oria, T Wiegand, J Escribano, A Elosegui-Artola… - Nature, 2017 - nature.com
Cells can sense the density and distribution of extracellular matrix (ECM) molecules by
means of individual integrin proteins and larger, integrin-containing adhesion complexes …

Studies on the mechanism of general anesthesia

MA Pavel, EN Petersen, H Wang, RA Lerner… - Proceedings of the …, 2020 - pnas.org
Inhaled anesthetics are a chemically diverse collection of hydrophobic molecules that
robustly activate TWIK-related K+ channels (TREK-1) and reversibly induce loss of …

Quantitative single-molecule localization microscopy

S Hugelier, PL Colosi… - Annual review of …, 2023 - annualreviews.org
Super-resolution fluorescence microscopy allows the investigation of cellular structures at
nanoscale resolution using light. Current developments in super-resolution microscopy have …

Single-molecule evaluation of fluorescent protein photoactivation efficiency using an in vivo nanotemplate

N Durisic, L Laparra-Cuervo, Á Sandoval-Álvarez… - Nature …, 2014 - nature.com
Photoswitchable fluorescent probes are central to localization-based super-resolution
microscopy. Among these probes, fluorescent proteins are appealing because they are …

Structural basis and functional role of intramembrane trimerization of the Fas/CD95 death receptor

Q Fu, TM Fu, AC Cruz, P Sengupta, SK Thomas… - Molecular cell, 2016 - cell.com
Summary Fas (CD95, Apo-1, or TNFRSF6) is a prototypical apoptosis-inducing death
receptor in the tumor necrosis factor receptor (TNFR) superfamily. While the extracellular …

Probing exchange pathways in one-dimensional aggregates with super-resolution microscopy

L Albertazzi, D Van Der Zwaag, CMA Leenders… - Science, 2014 - science.org
Supramolecular fibers are prominent structures in biology and chemistry. A quantitative
understanding of molecular exchange pathways in these one-dimensional aggregates was …