Corneal diseases are a leading cause of blindness with an estimated 10 million patients
diagnosed with bilateral corneal blindness worldwide. Corneal transplantation is highly …

Background Ocular surface burns can be caused by chemicals (alkalis and acids) or by
direct heat. Amniotic membrane transplantation (AMT) performed in the acute phase (day 0 …

We developed cell-free implants, comprising carbodiimide crosslinked recombinant human
collagen (RHC), to enable corneal regeneration by endogenous cell recruitment, to address …

In this study, an injectable, photocurable gelatin system, consisting of acrylated gelatin and
thiolated gelatin, with tunable mechanical, biodegradation, and biological properties was …

The severe worldwide shortage of donor organs, and severe pathologies placing patients at
high risk for rejecting conventional cornea transplantation, have left many corneal blind …

Corneal blindness is a major cause of blindness in the world and corneal transplantation is
the only widely accepted treatment to restore sight in these eyes. However, it is becoming …

Corneal scarring limits vision for millions of individuals worldwide. Corneal transplantation
(keratoplasty) is the standard of care for corneal opacity; however, it bears the risk of graft …

The implant–host interface is a critical element in guiding tissue or organ regeneration. We
previously developed hydrogels comprising interpenetrating networks of recombinant …

Corneas with severe pathologies have a high risk of rejection when conventionally grafted
with human donor tissues. In this early observational study, we grafted bioengineered …

Short collagen-like peptides (CLPs) are being proposed as alternatives to full-length
collagen for use in tissue engineering, on their own as soft hydrogels, or conjugated to …