Steroid avoidance or withdrawal for kidney transplant recipients
Background Steroid‐sparing strategies have been attempted in recent decades to avoid
morbidity from long‐term steroid intake among kidney transplant recipients. Previous …
morbidity from long‐term steroid intake among kidney transplant recipients. Previous …
Immunosuppressive drugs in kidney transplantation: impact on patient survival, and incidence of cardiovascular disease, malignancy and infection
R Marcén - Drugs, 2009 - Springer
Renal transplant recipients have increased mortality rates when compared with the general
population. The new immunosuppressive drugs have improved short-term patient survival …
population. The new immunosuppressive drugs have improved short-term patient survival …
[HTML][HTML] Reduced exposure to calcineurin inhibitors in renal transplantation
H Ekberg, H Tedesco-Silva, A Demirbas… - … England Journal of …, 2007 - Mass Medical Soc
Background Immunosuppressive regimens with the fewest possible toxic effects are
desirable for transplant recipients. This study evaluated the efficacy and relative toxic effects …
desirable for transplant recipients. This study evaluated the efficacy and relative toxic effects …
Consensus recommendations for use of maintenance immunosuppression in solid organ transplantation: Endorsed by the American College of Clinical Pharmacy …
J Nelson, N Alvey, L Bowman, J Schulte… - … : The Journal of …, 2022 - Wiley Online Library
Advances in maintenance immunosuppression over the past three decades have improved
solid organ transplantation outcomes dramatically. Uninterrupted access to …
solid organ transplantation outcomes dramatically. Uninterrupted access to …
A prospective, randomized, double-blind, placebo-controlled multicenter trial comparing early (7 day) corticosteroid cessation versus long-term, low-dose …
ES Woodle, MR First, J Pirsch, F Shihab… - Annals of …, 2008 - journals.lww.com
Objective: To compare outcomes with early corticosteroid withdrawal (CSWD) and chronic
low dose corticosteroid therapy (CCS). Summary Background Data: Final, 5-year results …
low dose corticosteroid therapy (CCS). Summary Background Data: Final, 5-year results …
Rabbit-ATG or basiliximab induction for rapid steroid withdrawal after renal transplantation (Harmony): an open-label, multicentre, randomised controlled trial
O Thomusch, M Wiesener, M Opgenoorth, A Pascher… - The Lancet, 2016 - thelancet.com
Background Standard practice for immunosuppressive therapy after renal transplantation is
quadruple therapy using antibody induction, low-dose tacrolimus, mycophenolate mofetil …
quadruple therapy using antibody induction, low-dose tacrolimus, mycophenolate mofetil …
Interleukin 2 receptor antagonists for kidney transplant recipients
Background Interleukin 2 receptor antagonists (IL2Ra) are used as induction therapy for
prophylaxis against acute rejection in kidney transplant recipients. Use of IL2Ra has …
prophylaxis against acute rejection in kidney transplant recipients. Use of IL2Ra has …
Therapeutic monitoring of calcineurin inhibitors for the nephrologist
J Schiff, E Cole, M Cantarovich - Clinical Journal of the American …, 2007 - journals.lww.com
The calcineurin inhibitors (CNI) cyclosporine and tacrolimus remain the backbone of
immunosuppression for most kidney transplant recipients. Despite many years of …
immunosuppression for most kidney transplant recipients. Despite many years of …
[HTML][HTML] A randomized, multicenter study of steroid avoidance, early steroid withdrawal or standard steroid therapy in kidney transplant recipients
F Vincenti, FP Schena, S Paraskevas, IA Hauser… - American journal of …, 2008 - Elsevier
In a randomized, open-label, multicenter study, de novo renal transplant patients received
no steroids (n= 112), steroids to day 7 (n= 115), or standard steroids (n= 109) with …
no steroids (n= 112), steroids to day 7 (n= 115), or standard steroids (n= 109) with …
[HTML][HTML] Immunosuppression with belatacept-based, corticosteroid-avoiding regimens in de novo kidney transplant recipients
R Ferguson, J Grinyo, F Vincenti, DB Kaufman… - American Journal of …, 2011 - Elsevier
Current immunosuppressive regimens in renal transplantation typically include calcineurin
inhibitors (CNIs) and corticosteroids, both of which have toxicities that can impair recipient …
inhibitors (CNIs) and corticosteroids, both of which have toxicities that can impair recipient …