The microgenderome revealed: sex differences in bidirectional interactions between the microbiota, hormones, immunity and disease susceptibility

R Vemuri, KE Sylvia, SL Klein, SC Forster… - Seminars in …, 2019 - Springer
Sex differences in immunity are well described in the literature and thought to be mainly
driven by sex hormones and sex-linked immune response genes. The gastrointestinal tract …

An Overview of Helicobacter pylori VacA Toxin Biology

NJ Foegeding, RR Caston, MS McClain, MD Ohi… - Toxins, 2016 - mdpi.com
The VacA toxin secreted by Helicobacter pylori enhances the ability of the bacteria to
colonize the stomach and contributes to the pathogenesis of gastric adenocarcinoma and …

Helicobacter pylori and Its Role in Gastric Cancer

VE Reyes - Microorganisms, 2023 - mdpi.com
Gastric cancer is a challenging public health concern worldwide and remains a leading
cause of cancer-related mortality. The primary risk factor implicated in gastric cancer …

The immune receptor NOD1 and kinase RIP2 interact with bacterial peptidoglycan on early endosomes to promote autophagy and inflammatory signaling

AT Irving, H Mimuro, TA Kufer, C Lo, R Wheeler… - Cell host & …, 2014 - cell.com
The intracellular innate immune receptor NOD1 detects Gram-negative bacterial
peptidoglycan (PG) to induce autophagy and inflammatory responses in host cells. To date …

Dynamic control of type I IFN signalling by an integrated network of negative regulators

RA Porritt, PJ Hertzog - Trends in immunology, 2015 - cell.com
Whereas type I interferons (IFNs) have critical roles in protection from pathogens, excessive
IFN responses contribute to pathology in both acute and chronic settings, pointing to the …

Helicobacter pylori VacA, a distinct toxin exerts diverse functionalities in numerous cells: An overview

N Chauhan, ACY Tay, BJ Marshall, U Jain - Helicobacter, 2019 - Wiley Online Library
Background Helicobacter pylori, gastric cancer‐causing bacteria, survive in their gastric
environment of more than 50% of the world population. The presence of H. pylori in the …

The impact of Helicobacter pylori infection, eradication therapy, and probiotics intervention on gastric microbiota in young adults

Z Yuan, S **ao, S Li, B Suo, Y Wang, L Meng… - …, 2021 - Wiley Online Library
Background The impact of probiotics on non‐Helicobacter pylori gastric microbiota and its
role in microbial restoration after eradication were relatively unknown. We aimed to explore …

Considerations for the analysis of bacterial membrane vesicles: methods of vesicle production and quantification can influence biological and experimental outcomes

NJ Bitto, L Zavan, EL Johnston, TP Stinear… - Microbiology …, 2021 - Am Soc Microbiol
Bacterial membrane vesicles (BMVs) are produced by all bacteria and facilitate a range of
functions in host-microbe interactions and pathogenesis. Quantification of BMVs is a critical …

[HTML][HTML] Immune evasion strategies used by Helicobacter pylori

TT Lina, S Alzahrani, J Gonzalez… - World journal of …, 2014 - ncbi.nlm.nih.gov
Helicobacter pylori (H. pylori) is perhaps the most ubiquitous and successful human
pathogen, since it colonizes the stomach of more than half of humankind. Infection with this …

[HTML][HTML] Helicobacter pylori infection: host immune response, implications on gene expression and microRNAs

ACT Cadamuro, AFT Rossi, NM Maniezzo… - World journal of …, 2014 - ncbi.nlm.nih.gov
Helicobacter pylori (H. pylori) infection is the most common bacterial infection worldwide.
Persistent infection of the gastric mucosa leads to inflammatory processes and may remain …