The microgenderome revealed: sex differences in bidirectional interactions between the microbiota, hormones, immunity and disease susceptibility
Sex differences in immunity are well described in the literature and thought to be mainly
driven by sex hormones and sex-linked immune response genes. The gastrointestinal tract …
driven by sex hormones and sex-linked immune response genes. The gastrointestinal tract …
An Overview of Helicobacter pylori VacA Toxin Biology
NJ Foegeding, RR Caston, MS McClain, MD Ohi… - Toxins, 2016 - mdpi.com
The VacA toxin secreted by Helicobacter pylori enhances the ability of the bacteria to
colonize the stomach and contributes to the pathogenesis of gastric adenocarcinoma and …
colonize the stomach and contributes to the pathogenesis of gastric adenocarcinoma and …
Helicobacter pylori and Its Role in Gastric Cancer
VE Reyes - Microorganisms, 2023 - mdpi.com
Gastric cancer is a challenging public health concern worldwide and remains a leading
cause of cancer-related mortality. The primary risk factor implicated in gastric cancer …
cause of cancer-related mortality. The primary risk factor implicated in gastric cancer …
The immune receptor NOD1 and kinase RIP2 interact with bacterial peptidoglycan on early endosomes to promote autophagy and inflammatory signaling
The intracellular innate immune receptor NOD1 detects Gram-negative bacterial
peptidoglycan (PG) to induce autophagy and inflammatory responses in host cells. To date …
peptidoglycan (PG) to induce autophagy and inflammatory responses in host cells. To date …
Dynamic control of type I IFN signalling by an integrated network of negative regulators
RA Porritt, PJ Hertzog - Trends in immunology, 2015 - cell.com
Whereas type I interferons (IFNs) have critical roles in protection from pathogens, excessive
IFN responses contribute to pathology in both acute and chronic settings, pointing to the …
IFN responses contribute to pathology in both acute and chronic settings, pointing to the …
Helicobacter pylori VacA, a distinct toxin exerts diverse functionalities in numerous cells: An overview
Background Helicobacter pylori, gastric cancer‐causing bacteria, survive in their gastric
environment of more than 50% of the world population. The presence of H. pylori in the …
environment of more than 50% of the world population. The presence of H. pylori in the …
The impact of Helicobacter pylori infection, eradication therapy, and probiotics intervention on gastric microbiota in young adults
Z Yuan, S **ao, S Li, B Suo, Y Wang, L Meng… - …, 2021 - Wiley Online Library
Background The impact of probiotics on non‐Helicobacter pylori gastric microbiota and its
role in microbial restoration after eradication were relatively unknown. We aimed to explore …
role in microbial restoration after eradication were relatively unknown. We aimed to explore …
Considerations for the analysis of bacterial membrane vesicles: methods of vesicle production and quantification can influence biological and experimental outcomes
Bacterial membrane vesicles (BMVs) are produced by all bacteria and facilitate a range of
functions in host-microbe interactions and pathogenesis. Quantification of BMVs is a critical …
functions in host-microbe interactions and pathogenesis. Quantification of BMVs is a critical …
[HTML][HTML] Immune evasion strategies used by Helicobacter pylori
TT Lina, S Alzahrani, J Gonzalez… - World journal of …, 2014 - ncbi.nlm.nih.gov
Helicobacter pylori (H. pylori) is perhaps the most ubiquitous and successful human
pathogen, since it colonizes the stomach of more than half of humankind. Infection with this …
pathogen, since it colonizes the stomach of more than half of humankind. Infection with this …
[HTML][HTML] Helicobacter pylori infection: host immune response, implications on gene expression and microRNAs
ACT Cadamuro, AFT Rossi, NM Maniezzo… - World journal of …, 2014 - ncbi.nlm.nih.gov
Helicobacter pylori (H. pylori) infection is the most common bacterial infection worldwide.
Persistent infection of the gastric mucosa leads to inflammatory processes and may remain …
Persistent infection of the gastric mucosa leads to inflammatory processes and may remain …