We used force-clamp atomic force micoscopy to measure the end-to-end length of the small
protein ubiquitin during its folding reaction at the single-molecule level. Ubiquitin was first …

The transition of a solvated flexible macromolecular chain from random coil behavior in the θ‐
state to a globular compact form in the collapsed state has been the subject of extensive …

The mammalian visual cortex is organized into columns. Here, we examine cortical
influences upon develo** visual afferents in the cat by altering intrinsic γ-aminobutyric …

Huntington's disease is linked to the insertion of glutamine (Q) in the protein huntingtin,
resulting in polyglutamine (polyQ) expansions that self-associate to form aggregates. While …

The stretching response of a single collapsed homopolymer is studied using Brownian
dynamic simulations. The irreversibly dissipated work is found to be dominated by internal …

Field-driven transport through nanofluidic devices has emerged as one of the promising
tools for characterizing the conformational and dynamical response of long polyelectrolytes …

We study the conformational dynamics within homopolymer globules by solvent-implicit
Brownian dynamics simulations. A strong dependence of the internal chain dynamics on the …

The crucial role of the biopolymer “Von Willebrand factor”(VWF) in blood platelet binding is
tightly regulated by the shear forces to which the protein is exposed in the blood flow. Under …

This paper presents a theoretical and simulation investigation into the force–extension
behavior of self-associating homopolymers. In particular, we show how long-lasting …

We present results of numerical self-consistent field (SCF) calculations for the equilibrium
mechanical unfolding of a globule formed by a single flexible polymer chain collapsed in a …