Near-infrared luminescence high-contrast in vivo biomedical imaging

Y Chen, S Wang, F Zhang - Nature Reviews Bioengineering, 2023 - nature.com
Luminescence imaging in biomedical research has allowed new insights into the
architecture of pathological tissues, signalling networks and cell interactions, and is now …

Design of therapeutic biomaterials to control inflammation

Z Tu, Y Zhong, H Hu, D Shao, R Haag… - Nature Reviews …, 2022 - nature.com
Inflammation plays an important role in the response to danger signals arising from damage
to our body and in restoring homeostasis. Dysregulated inflammatory responses occur in …

Tumor abnormality-oriented nanomedicine design

Q Zhou, J **ang, N Qiu, Y Wang, Y Piao, S Shao… - Chemical …, 2023 - ACS Publications
Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …

The tumor EPR effect for cancer drug delivery: Current status, limitations, and alternatives

R Sun, J **ang, Q Zhou, Y Piao, J Tang, S Shao… - Advanced Drug Delivery …, 2022 - Elsevier
Over the past three decades, the enhanced permeability and retention (EPR) effect has
been considered the basis of tumor-targeted drug delivery. Various cancer nanomedicines …

BODIPY as a Multifunctional Theranostic Reagent in Biomedicine: Self‐Assembly, Properties, and Applications

HB Cheng, X Cao, S Zhang, K Zhang… - Advanced …, 2023 - Wiley Online Library
The use of boron dipyrromethene (BODIPY) in biomedicine is reviewed. To open, its
synthesis and regulatory strategies are summarized, and inspiring cutting‐edge work in post …

Targeted drug delivery strategies for precision medicines

MT Manzari, Y Shamay, H Kiguchi, N Rosen… - Nature Reviews …, 2021 - nature.com
Progress in the field of precision medicine has changed the landscape of cancer therapy.
Precision medicine is propelled by technologies that enable molecular profiling, genomic …

Nanomedicine‐Enabled Sonomechanical, Sonopiezoelectric, Sonodynamic, and Sonothermal Therapy

X Song, Q Zhang, M Chang, L Ding… - Advanced …, 2023 - Wiley Online Library
Nanomedicine‐enabled/augmented ultrasound (US) medicine is a unique area of
interdisciplinary research that focuses on designing and engineering functional …

The use of alternative strategies for enhanced nanoparticle delivery to solid tumors

M Izci, C Maksoudian, BB Manshian… - Chemical …, 2021 - ACS Publications
Nanomaterial (NM) delivery to solid tumors has been the focus of intense research for over a
decade. Classically, scientists have tried to improve NM delivery by employing passive or …

The ancillary effects of nanoparticles and their implications for nanomedicine

EP Stater, AY Sonay, C Hart, J Grimm - Nature Nanotechnology, 2021 - nature.com
Nanoparticles are often engineered as a scaffolding system to combine targeting, imaging
and/or therapeutic moieties into a unitary agent. However, mostly overlooked, the …

Programmably controllable delivery of metastable ferrous ions for multiscale dynamic imaging guided photothermal primed chemodynamic therapy

X Zhang, S Lin, F Zhao, J Zhang, S Lei, F Bai… - Advanced …, 2023 - Wiley Online Library
Metallomodulation cell death strategies are extensively investigated for antitumor therapy,
such as cuproptosis, ferroptosis, and chemodynamic therapy (CDT). Undoubtedly, the …