Fifty shades of brain: a review on the mechanical testing and modeling of brain tissue

S Budday, TC Ovaert, GA Holzapfel… - … Methods in Engineering, 2020 - Springer
Brain tissue is not only one of the most important but also the most complex and compliant
tissue in the human body. While long underestimated, increasing evidence confirms that …

Mechanics of the brain: perspectives, challenges, and opportunities

A Goriely, MGD Geers, GA Holzapfel… - … and modeling in …, 2015 - Springer
The human brain is the continuous subject of extensive investigation aimed at
understanding its behavior and function. Despite a clear evidence that mechanical factors …

Mechanical characterization of human brain tissue

S Budday, G Sommer, C Birkl, C Langkammer… - Acta biomaterialia, 2017 - Elsevier
Mechanics are increasingly recognized to play an important role in modulating brain form
and function. Computational simulations are a powerful tool to predict the mechanical …

Mechanical properties of gray and white matter brain tissue by indentation

S Budday, R Nay, R De Rooij, P Steinmann… - Journal of the …, 2015 - Elsevier
The mammalian brain is composed of an outer layer of gray matter, consisting of cell bodies,
dendrites, and unmyelinated axons, and an inner core of white matter, consisting primarily of …

Dual-function injectable angiogenic biomaterial for the repair of brain tissue following stroke

LR Nih, S Gojgini, ST Carmichael, T Segura - Nature materials, 2018 - nature.com
Stroke is the primary cause of disability due to the brain's limited ability to regenerate
damaged tissue. After stroke, an increased inflammatory and immune response coupled …

Functional 3D neural mini‐tissues from printed gel‐based bioink and human neural stem cells

Q Gu, E Tomaskovic‐Crook, R Lozano… - Advanced …, 2016 - Wiley Online Library
Direct‐write printing of stem cells within biomaterials presents an opportunity to engineer
tissue for in vitro modeling and regenerative medicine. Here, a first example of constructing …

Magnetic resonance elastography: a review

YK Mariappan, KJ Glaser, RL Ehman - Clinical anatomy, 2010 - Wiley Online Library
Magnetic resonance elastography (MRE) is a rapidly develo** technology for
quantitatively assessing the mechanical properties of tissue. The technology can be …

The mechanobiology of brain function

WJ Tyler - Nature Reviews Neuroscience, 2012 - nature.com
All cells are influenced by mechanical forces. In the brain, force-generating and load-
bearing proteins twist, turn, ratchet, flex, compress, expand and bend to mediate neuronal …

Magnetic resonance elastography (MRE) of the human brain: technique, findings and clinical applications

LV Hiscox, CL Johnson, E Barnhill… - Physics in Medicine …, 2016 - iopscience.iop.org
Neurological disorders are one of the most important public health concerns in developed
countries. Established brain imaging techniques such as magnetic resonance imaging (MRI) …

Physics of MRI: a primer

DB Plewes, W Kucharczyk - Journal of magnetic resonance …, 2012 - Wiley Online Library
This article is based on an introductory lecture given for the past many years during the “MR
Physics and Techniques for Clinicians” course at the Annual Meeting of the ISMRM. This …