Microfluidic approaches for cancer cell detection, characterization, and separation
This article reviews the recent developments in microfluidic technologies for in vitro cancer
diagnosis. We summarize the working principles and experimental results of key microfluidic …
diagnosis. We summarize the working principles and experimental results of key microfluidic …
Biomechanical characterization at the cell scale: present and prospects
The rapidly growing field of mechanobiology demands for robust and reproducible
characterization of cell mechanical properties. Recent achievements in understanding the …
characterization of cell mechanical properties. Recent achievements in understanding the …
Studying genomic processes at the single-molecule level: introducing the tools and applications
To understand genomic processes such as transcription, translation or splicing, we need to
be able to study their spatial and temporal organization at the molecular level. Single …
be able to study their spatial and temporal organization at the molecular level. Single …
Nanowire arrays as cell force sensors to investigate adhesin-enhanced holdfast of single cell bacteria and biofilm stability
Surface attachment of a planktonic bacteria, mediated by adhesins and extracellular
polymeric substances (EPS), is a crucial step for biofilm formation. Some pathogens can …
polymeric substances (EPS), is a crucial step for biofilm formation. Some pathogens can …
Modeling tumor microenvironments in vitro
Tumor progression depends critically upon the interactions between the tumor cells and
their microenvironment. The tumor microenvironment is heterogeneous and dynamic; it …
their microenvironment. The tumor microenvironment is heterogeneous and dynamic; it …
Modeling and analysis of conical-shaped notch flexure hinges based on NURBS
J Wu, Y Zhang, S Cai, J Cui - Mechanism and Machine Theory, 2018 - Elsevier
An analytical compliance matrix model of a flexure hinge is established and the conical-
shaped notch flexure hinge is innovatively parameterized using the non-uniform rational B …
shaped notch flexure hinge is innovatively parameterized using the non-uniform rational B …
MEMS-based platforms for mechanical manipulation and characterization of cells
Mechanical manipulation and characterization of single cells are important experimental
techniques in biological and medical research. Because of the microscale sizes and highly …
techniques in biological and medical research. Because of the microscale sizes and highly …
Evaluating Young's modulus of single yeast cells based on compression using an atomic force microscope with a flat tip
D Chang, T Hirate, C Uehara… - Microscopy and …, 2021 - academic.oup.com
In this research, atomic force microscopy (AFM) with a flat tip cantilever is utilized to measure
Young's modulus of a whole yeast cell (Saccharomyces cerevisiae BY4741). The results …
Young's modulus of a whole yeast cell (Saccharomyces cerevisiae BY4741). The results …
On-chip method to measure mechanical characteristics of a single cell by using moiré fringe
We propose a method to characterize the mechanical properties of cells using a robot-
integrated microfluidic chip (robochip) and microscopy. The microfluidic chip is designed to …
integrated microfluidic chip (robochip) and microscopy. The microfluidic chip is designed to …
Laser additive manufacturing processes for near net shape components
Laser-based additive manufacturing is a group of manufacturing processes widely used to
produce three-dimensional near net shape components. Lasers can provide localized and …
produce three-dimensional near net shape components. Lasers can provide localized and …