Osteoarthritis (OA) is unquestionably one of the most important chronic health issues in
humans, affecting millions of individuals and costing billions of dollars annually. Despite …

Osteoarthritis (OA) is one of the most common musculoskeletal diseases, caused by cellular
inflammatory responses and subsequent structural disruption in osteochondral extracellular …

Commencing with the breakdown of immune tolerance, multiple pathogenic factors,
including synovial inflammation and harmful cytokines, are conjointly involved in the …

The synovial tissues under rheumatoid arthritis conditions are usually infiltrated by
inflammatory cells, particularly M1 macrophages with aberrant redox homeostasis, which …

Poor O2 supply to the infiltrated immune cells in the joint synovium of rheumatoid arthritis
(RA) up-regulates hypoxia-inducible factor (HIF-1α) expression and induces reactive oxygen …

Osteoarthritis (OA) is a chronic degenerative disease of articular cartilage that is the most
common joint disease worldwide. Mesenchymal stem cells (MSCs) have been the most …

Osteoarthritis is a debilitating joint disease affecting nearly 30 million people for which there
are no disease-modifying therapies. Several drugs that have failed clinical trials have shown …

Background Osteoarthritis (OA) is a common and debilitating chronic degenerative disease
of the joints. Currently, cell-based therapy is being explored to address the repair of …

Osteoarthritis (OA), characterized by progressive destruction of articular cartilage, is the most
common form of human arthritis. Here, we evaluated the potential chondroprotective and …

The emerging 3D bioprinting technique that is strongly dependent on the development of
bioinks offers a promising opportunity to customize personalized bioscaffolds for precision …