A comprehensive review on polyelectrolyte complexes

VS Meka, MKG Sing, MR Pichika, SR Nali… - Drug discovery today, 2017 - Elsevier
Highlights•Polyelectrolytes are a type of polymer having multitudinous ionizable functional
groups.•Polyelectrolytes have become one of the most attractive subjects of scientific …

[HTML][HTML] Membrane-disruptive peptides/peptidomimetics-based therapeutics: Promising systems to combat bacteria and cancer in the drug-resistant era

L Lin, J Chi, Y Yan, R Luo, X Feng, Y Zheng… - … Pharmaceutica Sinica B, 2021 - Elsevier
Membrane-disruptive peptides/peptidomimetics (MDPs) are antimicrobials or
anticarcinogens that present a general killing mechanism through the physical disruption of …

Synergistic photodynamic and photothermal antibacterial nanocomposite membrane triggered by single NIR light source

J Sun, L Song, Y Fan, L Tian, S Luan… - … applied materials & …, 2019 - ACS Publications
Herein, we developed a nanocomposite membrane with synergistic photodynamic therapy
and photothermal therapy antibacterial effects, triggered by a single near-infrared (NIR) light …

Emerging antibacterial nanomedicine for enhanced antibiotic therapy

S Wang, Y Gao, Q **, J Ji - Biomaterials Science, 2020 - pubs.rsc.org
Antibiotic therapy is the most powerful strategy for treating bacterial infections in clinic.
However, antibiotic resistance has become one of the biggest threats to public health …

Current advances in lipid and polymeric antimicrobial peptide delivery systems and coatings for the prevention and treatment of bacterial infections

ME van Gent, M Ali, PH Nibbering, SN Kłodzińska - Pharmaceutics, 2021 - mdpi.com
Bacterial infections constitute a threat to public health as antibiotics are becoming less
effective due to the emergence of antimicrobial resistant strains and biofilm and persister …

Toxicity effects of functionalized quantum dots, gold and polystyrene nanoparticles on target aquatic biological models: a review

G Libralato, E Galdiero, A Falanga, R Carotenuto… - Molecules, 2017 - mdpi.com
Nano-based products are widespread in several sectors, including textiles, medical-
products, cosmetics, paints and plastics. Nanosafety and safe-by-design are driving …

An inflammation-targeted nanoparticle with bacteria forced release of polymyxin B for pneumonia therapy

P Zhang, Q Ouyang, T Zhai, J Sun, J Wu, F Qin… - Nanoscale, 2022 - pubs.rsc.org
The epidemic of multidrug-resistant Gram-negative bacteria is an ever-growing global
concern. Polymyxin B (PMB), a kind of “old fashioned” antibiotic, has been revived in clinical …

Polymyxin B‐polysaccharide polyion nanocomplex with improved biocompatibility and unaffected antibacterial activity for acute lung infection management

M Chai, Y Gao, J Liu, Y Deng, D Hu… - Advanced Healthcare …, 2020 - Wiley Online Library
The decade‐old antibiotic, polymyxin B (PMB), is regarded as the last line defense against
gram‐negative “superbug.” However, the serious nephrotoxicity and neurotoxicity strongly …

Design of mucoadhesive gellan gum and chitosan nanoparticles intended for colon-specific delivery of peptide drugs

VM de Oliveira Cardoso, NAP de Brito… - Colloids and Surfaces A …, 2021 - Elsevier
Nanotechnology has been widely used in the development of polymer nanocarriers for the
oral delivery of biomolecules. The use of nanostructured systems can improve drug delivery …

Recent advances in oral mucoadhesive drug delivery

S Golshani, A Vatanara, M Amin - Journal of Pharmacy & …, 2022 - journals.library.ualberta.ca
The oral cavity is one of the most important routes for local and systemic drug delivery, as it
has a large surface, high permeability, and rich blood supply. Oral mucosal drug delivery …