[HTML][HTML] Emerging artificial intelligence (AI) technologies used in the development of solid dosage forms

J Jiang, X Ma, D Ouyang, RO Williams III - Pharmaceutics, 2022 - mdpi.com
Artificial Intelligence (AI)-based formulation development is a promising approach for
facilitating the drug product development process. AI is a versatile tool that contains multiple …

Microstructure formation and characterization of long-acting injectable microspheres: the gateway to fully controlled drug release pattern

M Wang, S Wang, C Zhang, M Ma, B Yan… - International Journal …, 2024 - Taylor & Francis
Long-acting injectable microspheres have been on the market for more than three decades,
but if calculated on the brand name, only 12 products have been approved by the FDA due …

In silico formulation optimization and particle engineering of pharmaceutical products using a generative artificial intelligence structure synthesis method

T Hornick, C Mao, A Koynov, P Yawman… - Nature …, 2024 - nature.com
Pharmaceutical drug dosage forms are critical for ensuring the effective and safe delivery of
active pharmaceutical ingredients to patients. However, traditional formulation development …

Focused ion beam-scanning electron microscopy provides novel insights of drug delivery phenomena

T Faber, JT McConville, A Lamprecht - Journal of Controlled Release, 2024 - Elsevier
Scanning electron microscopy (SEM) has long been a standard tool for morphological
analyses, providing sub micrometer resolution of pharmaceutical formulations. However …

[HTML][HTML] Betaine-urea deep eutectic solvent improves imipenem antibiotic activity

B Olivares, FA Martínez, M Ezquer, BJ Morales… - Journal of Molecular …, 2022 - Elsevier
Beta-lactam antibiotics are highly unstable in aqueous media, which may lead to subclinical
concentrations, antimicrobial resistance and therapeutic failure. In previous work we …

[HTML][HTML] Application of an AI image analysis and classification approach to characterise dissolution and precipitation events in the flow through apparatus

AR Taseva, T Persoons, DM D'Arcy - European Journal of Pharmaceutics …, 2023 - Elsevier
Imaging and artificial intelligence (AI) approaches have been used with increasing
frequency in pharmaceutical industry in recent years. Characterisation of processes such as …

Quantitative Structural and Compositional Elucidation of Real-World Pharmaceutical Tablet Using Large Field-of-View, Correlative Microscopy-Tomography …

Y Chen, S Baviriseaty, P Thool, J Gautreau… - Pharmaceutical …, 2025 - Springer
Purpose The purpose of this study is to present a correlative microscopy-tomography
approach in conjunction with machine learning-based image segmentation techniques, with …

In-situ 3D X-ray tomography and analysis of reverse osmosis membranes under compaction

Y Suleiman, N May, M Zhang, A Zhu… - Microscopy and …, 2022 - cambridge.org
The need for attention to freshwater protection and management is rising as water scarcity
becomes more prevalent in the coming years. The water treatment process of reverse …

Overcoming challenges of solid dosage formulation development by using emerging technologies

J Jiang - 2023 - repositories.lib.utexas.edu
Solid dosage forms, such as tablets, capsules, and powder, are one of the most widely used
administration methods for drug delivery. However, scientists and researchers are facing …