Magnetic resonance (MR) is a powerful technique for noninvasively probing molecular
species in vivo but suffers from low signal sensitivity. Saturation transfer (ST) MRI …

The ability of CEST MRI to detect the presence of millimolar concentrations of non‐metallic
contrast agents has made it possible to study, non‐invasively, important biological …

Purpose To develop a steady‐state saturation with radial readout chemical exchange
saturation transfer (starCEST) for acquiring CEST images at 3 Tesla (T). The polynomial …

The liver plays a central role in metabolic homeostasis, as exemplified by a variety of clinical
disorders with hepatic and systemic metabolic disarrays. Of particular interest are the …

Access to metabolic information in vivo using magnetic resonance (MR) technologies has
generally been the niche of MR spectroscopy (MRS) and spectroscopic imaging (MRSI) …

Glycogen is a biologically essential macromolecule that is directly involved in multiple
human diseases. While its primary role in carbohydrate storage and energy metabolism in …

Nuclear magnetic resonance (NMR) spectroscopy serves as a robust non-invasive
characterization technique for probing molecular structure and providing quantitative …

Purpose The pH sensitivity of chemical exchange‐relayed nuclear Overhauser
enhancement (rNOE) signal in a saturation transfer experiment is not fully understood and …

Chemical exchange saturation transfer (CEST) MRI is a promising molecular imaging tool
which allows the specific detection of metabolites that contain exchangeable amide, amine …

Purpose Glycogen storage disease type III (GSD III) is a rare inherited metabolic disease
characterized by excessive accumulation of glycogen in liver, skeletal muscle, and heart …