The vast majority of the genetic variants (mainly SNPs) associated with various human traits
and diseases map to a noncoding part of the genome and are enriched in its regulatory …

The burden of human disease lies predominantly in polygenic diseases. Since the early
2000s, genome-wide association studies (GWAS) have identified genetic variants and loci …

Most of the millions of SNPs in the human genome are non-coding, and many overlap with
putative regulatory elements. Genome-wide association studies (GWAS) have linked many …

Abstract “Test‐and‐go” single‐nucleotide variation (SNV) detection within several minutes
remains challenging, especially in low‐abundance samples, since existing methods face a …

The dynamic liquid environment of live cells makes it necessary to consider the surface
wettability when designing biomaterials and related devices. Especially superwettability, as …

Androgen receptor (AR) drives prostate cancer (PCa) development and progression. AR
chromatin binding profiles are highly plastic and form recurrent programmatic changes that …

Massive DNA testing requires novel technologies to support a sustainable health system. In
recent years, DNA superstructures have emerged as alternative probes and transducers …

Lysine 2-hydroxyisobutyrylation is a novel detected post translational modification type in
the research of proteomics. Such modification research may be helpful to several diseases' …

Monitoring diseases caused by pathogens or by mutations in DNA sequences requires
accurate, rapid, and sensitive tools to detect specific nucleic acid sequences. Here, we …

There is growing evidence that a wide range of human diseases and physiological traits are
influenced by genetic variation of cis-regulatory elements. We and others have shown that a …