Cells actively sense and process mechanical information that is provided by the extracellular
environment to make decisions about growth, motility and differentiation. It is important to …

The stiffness and nanotopographical characteristics of the extracellular matrix (ECM)
influence numerous developmental, physiological, and pathological processes in vivo …

This essay analyzes the scientific evidence that forms the basis of bioactive materials,
covering the fundamental understanding of bioactivity phenomena and correlation with the …

Advancements in the field of tissue engineering have led to the elucidation of physical and
chemical characteristics of physiological basement membranes (BM) as specialized forms of …

Tissue engineering is a promising therapeutic approach in medicine, targeting the
replacement of a diseased tissue with a healthy one grown within an artificial scaffold. Due …

Mechanobiology has underpinned many scientific advances in understanding how
biophysical and biomechanical cues regulate cell behavior by identifying mechanosensitive …

The advancement achieved in Tissue Engineering is based on a careful and in-depth study
of cell–tissue interactions. The choice of a specific biomaterial in Tissue Engineering is …

The cross-talk between stem cells and their microenvironment has been shown to have a
direct impact on stem cells' decisions about proliferation, growth, migration, and …

Adult stem cell research has been advanced in recent years because of the cells' attractive
abilities of self-renewal and differentiation. Topography of materials is one of the key …

Scar formation resulting from burns or severe trauma can significantly compromise the
structural integrity of skin and lead to permanent loss of skin appendages, ultimately …