Advances in genomics have led to mounting expectations in regard to their impact on health
care and disease prevention. In light of this fact, a comprehensive research agenda is …

Purpose: To review information on the use of laboratory tests in screening, diagnosis, and
monitoring of acute and chronic hepatic injury. Data Sources and Study Selection: A …

Objective To compare prevalent and incident morbidity and mortality between those with the
HFE p. C282Y genetic variant (responsible for most hereditary haemochromatosis type 1) …

The history of biology was forever altered a decade ago by the bold decision to launch a
research program that would characterize in ultimate detail the complete set of genetic …

Hereditary hemochromatosis (HHC) is an autosomal recessive disorder of iron metabolism
characterized by increased iron absorption and deposition in the liver, pancreas, heart …

Background and Methods Hereditary hemochromatosis is associated with homozygosity for
the C282Y mutation in the hemochromatosis (HFE) gene on chromosome 6, elevated serum …

Newborns are now routinely screened for the presence of a number of inherited diseases. In
these cases, early diagnosis allows treatment to be instituted before there are irreversible …

A masterful guide to human development that redefines the nature versus nurture debate A
much-needed antidote to genetic determinism, The Dependent Gene reveals how all traits …

Background: Hereditary hemochromatosis (HH) is a common genetic disease leading to
accumulation of iron in several organs, most notably the liver. The C282Y/C282Y mutation in …

Predictive genetic testing is the use of a genetic test in an asymptomatic person to predict
future risk of disease. These tests represent a new and growing class of medical tests …