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[HTML][HTML] Breast cancer metastasis: mechanisms and therapeutic implications
Breast cancer is the most common malignancy in women worldwide. Metastasis is the
leading cause of high mortality in most cancers. Although predicting the early stage of breast …
leading cause of high mortality in most cancers. Although predicting the early stage of breast …
[HTML][HTML] The role of tumor-associated macrophages in the progression and chemoresistance of ovarian cancer
M Nowak, M Klink - Cells, 2020 - mdpi.com
Tumor-associated macrophages (TAMs) constitute the main population of immune cells
present in the ovarian tumor microenvironment. These cells are characterized by high …
present in the ovarian tumor microenvironment. These cells are characterized by high …
Spatial transcriptomics depict ligand–receptor cross-talk heterogeneity at the tumor-stroma interface in long-term ovarian cancer survivors
Advanced high-grade serous ovarian cancer (HGSC) is an aggressive disease that
accounts for 70% of all ovarian cancer deaths. Nevertheless, 15% of patients diagnosed …
accounts for 70% of all ovarian cancer deaths. Nevertheless, 15% of patients diagnosed …
Interferon-ε is a tumour suppressor and restricts ovarian cancer
High-grade serous ovarian cancers have low survival rates because of their late
presentation with extensive peritoneal metastases and frequent chemoresistance, and …
presentation with extensive peritoneal metastases and frequent chemoresistance, and …
An evolving story of the metastatic voyage of ovarian cancer cells: cellular and molecular orchestration of the adipose-rich metastatic microenvironment
Metastasis is a complex multistep process that involves critical interactions between cancer
cells and a variety of stromal components in the tumor microenvironment, which profoundly …
cells and a variety of stromal components in the tumor microenvironment, which profoundly …
Current insights into the metastasis of epithelial ovarian cancer-hopes and hurdles
Background Ovarian cancer is the most lethal gynecologic cancer and the fifth leading
cause of cancer-related mortality in women worldwide. Despite various attempts to improve …
cause of cancer-related mortality in women worldwide. Despite various attempts to improve …
Omental macrophages secrete chemokine ligands that promote ovarian cancer colonization of the omentum via CCR1
The omentum is the most common site of ovarian cancer metastasis. Immune cell clusters
called milky spots are found throughout the omentum. It is however unknown if these …
called milky spots are found throughout the omentum. It is however unknown if these …
Hormonal therapy for gynecological cancers: how far has science progressed toward clinical applications?
Simple Summary The most common therapies for severe and recurrent gynecological
cancers are hormone therapy and chemotherapy, and responsiveness to therapy is a key …
cancers are hormone therapy and chemotherapy, and responsiveness to therapy is a key …
Screening drug effects in patient‐derived cancer cells links organoid responses to genome alterations
Cancer drug screening in patient‐derived cells holds great promise for personalized
oncology and drug discovery but lacks standardization. Whether cells are cultured as …
oncology and drug discovery but lacks standardization. Whether cells are cultured as …
Liquid biopsy in ovarian cancer: the potential of circulating miRNAs and exosomes
Ovarian cancer still remains the most lethal female cancer, since in most cases it is
diagnosed at an advanced stage. Usually after completion of primary treatment …
diagnosed at an advanced stage. Usually after completion of primary treatment …