T cells in the immune system protect the human body from infection by pathogens and clear
mutant cells through specific recognition by T cell receptors (TCRs). Cancer immunotherapy …

The intrinsic property of cell-penetrating peptides (CPPs) to deliver therapeutic molecules
(nucleic acids, drugs, imaging agents) to cells and tissues in a nontoxic manner has …

It is now well accepted that plasma cells can become long-lived (memory) plasma cells and
secrete antibodies for months, years or a lifetime. However, the mechanisms involved in this …

Antimicrobial host defense peptides are produced by all complex organisms as well as
some microbes and have diverse and complex antimicrobial activities. Collectively these …

Summary On July 1, 2014, the United States Food and Drug Administration granted
'breakthrough therapy'designation to CTL 019, the anti‐CD 19 chimeric antigen receptor T …

▪ Abstract The heparan sulfate on the surface of all adherent cells modulates the actions of a
large number of extracellular ligands. Members of both cell surface heparan sulfate …

Heparin, a sulfated polysaccharide belonging to the family of glycosaminoglycans, has
numerous important biological activities, associated with its interaction with diverse proteins …

Chemokines direct the trafficking of white blood cells in immune surveillance, playing a key
role in inflammatory and infectious diseases such as AIDS1–5. All chemokines studied so far …

The human parvovirus adeno-associated virus (AAV) infects a broad range of cell types,
including human, nonhuman primate, canine, murine, and avian. Although little is known …

▪ Abstract Virtually every cell type in metazoan organisms produces heparan sulfate. These
complex polysaccharides provide docking sites for numerous protein ligands and receptors …