Synthesis, antiproliferative effect and in silico LogP prediction of BIM-23052 analogs containing tyr instead of phe
(1) Background: Hydrophobicity (or lipophilicity) is a limiting factor in the ability of molecules
to pass through cell membranes and to perform their function. The ability to efficiently access …
to pass through cell membranes and to perform their function. The ability to efficiently access …
Solubility of N-(9-fluorenylmethoxycarbonyloxy)-succinimide in several aqueous co-solvent solutions revisited: Solvent effect, preferential solvation and dissolution …
F Zhang, J Yang, H Liu - Journal of Molecular Liquids, 2021 - Elsevier
Abstract Preferential solvation of N-(9-fluorenylmethoxycarbonyloxy)-succinimide (Fmoc-
OSu) in mixtures of DMF (1)+ water (2), ethanol (1)+ water (2), ethylene glycol (EG, 1)+ water …
OSu) in mixtures of DMF (1)+ water (2), ethanol (1)+ water (2), ethylene glycol (EG, 1)+ water …
[PDF][PDF] SYNTHESIS OF NEW TRIAZOLE AND THIADIAZOLE DERIVATIVES OF THE N, N'-DISUBSTITUTED BENZIMIDAZOLE-2-THIONE AND EVALUATION OF …
In the present study series of triazole-, thiadiazole-and thiosemicarbazone-benzimidazole
hybrid compounds were synthesized as potential anti-cancer agents. In order to determine …
hybrid compounds were synthesized as potential anti-cancer agents. In order to determine …
Synthesis, Anticancer Activity, Docking Calculations and Hydrolytic Stability Studies of Bioconjugates of Monofluorenated Analogue of BIM-23052
Background: The fight against cancer has started since its discovery and has not subsided to
nowadays. Currently, the hybrid molecules have become a promising alternative to the …
nowadays. Currently, the hybrid molecules have become a promising alternative to the …
Optimised three-dimensional in vitro retinoblastoma models tailored for drug discovery and clinical translatability
I Sinenko - 2023 - infoscience.epfl.ch
Retinoblastoma, while relatively rare, stands as the most prevalent intraocular cancer. In
Switzerland, the survival rate approaches 100%, but it drops to less than 50% in low-income …
Switzerland, the survival rate approaches 100%, but it drops to less than 50% in low-income …
Synthesis of Peptide Molecules, Analogues of Lactoferricin and In Vitro Screening for Antimicrobial and Antitumor Activity
G Georgieva - 2023 - search.proquest.com
Antibiotic resistance and the increasing number of diagnosed oncological diseases affect all
areas of healthcare, drain the economy, and impact society. The leading importance of …
areas of healthcare, drain the economy, and impact society. The leading importance of …
Synthesis of Peptide Molecules, Analogues of Lactoferricin and in Vitro Screening for Antimicrobial and Antitumor Activity//Синтезиране на пептидни молекули …
ДД Георгиева - 2023 - repository.mu-varna.bg
Антибиотичната резистентност и нарастващия брой диагностицирани онкологични
заболявания, засягат всички сфери на здравеопазването, изтощава икономиката и има …
заболявания, засягат всички сфери на здравеопазването, изтощава икономиката и има …
[PDF][PDF] Synthesis, Antiproliferative Effect and In Silico LogP Prediction of BIM-23052 Analogs Containing Tyr Instead of Phe. Pharmaceutics 2023, 15, 1123
D Danalev, I Iliev, S Dobrev, S Angelova, S Petrin… - 2023 - researchgate.net
(1) Background: Hydrophobicity (or lipophilicity) is a limiting factor in the ability of molecules
to pass through cell membranes and to perform their function. The ability to efficiently access …
to pass through cell membranes and to perform their function. The ability to efficiently access …
[PDF][PDF] A holistic Approach for Target Therapy of Cancer
D Danalev, D Borisova, I Iliev, I Sulikovska… - Colloid and interface … - extreme-esn.eu
One of the major problems in cancer chemotherapy is that the applied drugs are not
selective in regards to cancer and normal cells. The damage of normal cells leads to …
selective in regards to cancer and normal cells. The damage of normal cells leads to …