Hypothalamic–pituitary–adrenal and hypothalamic–pituitary–gonadal axes: sex differences in regulation of stress responsivity

MG Oyola, RJ Handa - stress, 2017‏ - Taylor & Francis
Gonadal hormones play a key role in the establishment, activation, and regulation of the
hypothalamic–pituitary–adrenal (HPA) axis. By influencing the response and sensitivity to …

The social salience hypothesis of oxytocin

SG Shamay-Tsoory, A Abu-Akel - Biological psychiatry, 2016‏ - Elsevier
Oxytocin is a nonapeptide that also serves as a neuromodulator in the human central
nervous system. Over the last decade, a sizeable body of literature has examined its effects …

Oxytocin and vasopressin in the human brain: social neuropeptides for translational medicine

A Meyer-Lindenberg, G Domes, P Kirsch… - Nature Reviews …, 2011‏ - nature.com
The neuropeptides oxytocin (OXT) and arginine vasopressin (AVP) are evolutionarily highly
conserved mediators in the regulation of complex social cognition and behaviour. Recent …

Social effects of oxytocin in humans: context and person matter

JA Bartz, J Zaki, N Bolger, KN Ochsner - Trends in cognitive sciences, 2011‏ - cell.com
Building on animal research, the past decade has witnessed a surge of interest in the effects
of oxytocin on social cognition and prosocial behavior in humans. This work has generated …

The adaptive calibration model of stress responsivity

M Del Giudice, BJ Ellis, EA Shirtcliff - Neuroscience & biobehavioral reviews, 2011‏ - Elsevier
This paper presents the Adaptive Calibration Model (ACM), an evolutionary–developmental
theory of individual differences in the functioning of the stress response system. The stress …

Consensus paper: pathological role of the cerebellum in autism

SH Fatemi, KA Aldinger, P Ashwood, ML Bauman… - The Cerebellum, 2012‏ - Springer
There has been significant advancement in various aspects of scientific knowledge
concerning the role of cerebellum in the etiopathogenesis of autism. In the current …

Biobehavioral responses to stress in females: Tend-and-befriend, not fight-or-flight

SE Taylor, LC Klein, BP Lewis, TL Gruenewald… - 2002‏ - direct.mit.edu
Background The fight-or-flight response is generally regarded as the prototypic human
response to stress. First described by Walter Cannon in 1932, the fightor-flight response is …

The oxytocin receptor system: structure, function, and regulation

G Gimpl, F Fahrenholz - Physiological reviews, 2001‏ - journals.physiology.org
The neurohypophysial peptide oxytocin (OT) and OT-like hormones facilitate reproduction in
all vertebrates at several levels. The major site of OT gene expression is the magnocellular …

Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations

MJ Meaney - Annual review of neuroscience, 2001‏ - annualreviews.org
▪ Abstract Naturally occurring variations in maternal care alter the expression of genes that
regulate behavioral and endocrine responses to stress, as well as hippocampal synaptic …

Oxytocin: the great facilitator of life

HJ Lee, AH Macbeth, JH Pagani, WS Young 3rd - Progress in neurobiology, 2009‏ - Elsevier
Oxytocin (Oxt) is a nonapeptide hormone best known for its role in lactation and parturition.
Since 1906 when its uterine-contracting properties were described until 50 years later when …