The insula: an underestimated brain area in clinical neuroscience, psychiatry, and neurology

H Namkung, SH Kim, A Sawa - Trends in neurosciences, 2017 - cell.com
Supported by recent human neuroimaging studies, the insula is re-emerging as an important
brain area not only in the physiological understanding of the brain, but also in pathological …

Emotional valence modulates brain functional abnormalities in depression: evidence from a meta-analysis of fMRI studies

NA Groenewold, EM Opmeer, P de Jonge… - Neuroscience & …, 2013 - Elsevier
Models describing the neural correlates of biased emotion processing in depression have
focused on increased activation of anterior cingulate and amygdala and decreased …

Facial emotion processing in major depression: a systematic review of neuroimaging findings

A Stuhrmann, T Suslow, U Dannlowski - Biology of mood & anxiety …, 2011 - Springer
Background Cognitive models of depression suggest that major depression is characterized
by biased facial emotion processing, making facial stimuli particularly valuable for …

Where in the brain is depression?

M Pandya, M Altinay, DA Malone, A Anand - Current psychiatry reports, 2012 - Springer
Major depressive disorder is a serious medical illness which is responsible for considerable
morbidity and disability. Despite decades of research, the neural basis for depression is still …

Meta-analysis of reward processing in major depressive disorder reveals distinct abnormalities within the reward circuit

TH Ng, LB Alloy, DV Smith - Translational psychiatry, 2019 - nature.com
Many neuroimaging studies have investigated reward processing dysfunction in major
depressive disorder. These studies have led to the common idea that major depressive …

Depression uncouples brain hate circuit

H Tao, S Guo, T Ge, KM Kendrick, Z Xue, Z Liu… - Molecular …, 2013 - nature.com
It is increasingly recognized that we need a better understanding of how mental disorders
such as depression alter the brain's functional connections to improve both early diagnosis …

Systematic review of the neural basis of social cognition in patients with mood disorders

AM Cusi, A Nazarov, K Holshausen… - Journal of Psychiatry and …, 2012 - jpn.ca
Background: This review integrates neuroimaging studies of 2 domains of social cognition—
emotion comprehension and theory of mind (ToM)—in patients with major depressive …

Major depressive disorder and alterations in insular cortical activity: a review of current functional magnetic imaging research

D Sliz, S Hayley - Frontiers in human neuroscience, 2012 - frontiersin.org
Major depressive disorder (MDD) is characterized by a dysregulated fronto-limbic network.
The hyperactivation of limbic regions leads to increased attention and processing of …

Facial expression recognition: A meta-analytic review of theoretical models and neuroimaging evidence

P Xu, S Peng, Y Luo, G Gong - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
Discrimination of facial expressions is an elementary function of the human brain. While the
way emotions are represented in the brain has long been debated, common and specific …

Functions of the anterior insula in taste, autonomic, and related functions

ET Rolls - Brain and cognition, 2016 - Elsevier
The anterior insula contains the primary taste cortex, in which neurons in primates respond
to different combinations providing a distributed representation of different prototypical …