ATP in current biotechnology: regulation, applications and perspectives

J Zhou, L Liu, Z Shi, G Du, J Chen - Biotechnology advances, 2009 - Elsevier
Adenosine tri-phosphate (ATP), the most important energy source for metabolic reactions
and pathways, plays a vital role in the growth of industrial strain and the production of target …

A flux-sensing mechanism could regulate the switch between respiration and fermentation

DHEW Huberts, B Niebel, M Heinemann - FEMS yeast research, 2012 - academic.oup.com
The yeast Saccharomyces cerevisiae can show different metabolic phenotypes (eg
fermentation and respiration). Based on data from the literature, we argue that the substrate …

Hydroxyurea arrests DNA replication by a mechanism that preserves basal dNTP pools

A Koç, LJ Wheeler, CK Mathews, GF Merrill - Journal of Biological …, 2004 - ASBMB
The relationship between dNTP levels and DNA synthesis was investigated using α factor-
synchronized yeast treated with the ribonucleotide reductase inhibitor hydroxyurea (HU) …

Effect of temperature on metabolic activity of intact microbial communities: evidence for altered metabolic pathway activity but not for increased maintenance …

P Dijkstra, SC Thomas, PL Heinrich, GW Koch… - Soil Biology and …, 2011 - Elsevier
We used metabolic tracers and modeling to analyze the response of soil metabolism to a
sudden change in temperature from 4 to 20° C. We hypothesized that intact soil microbial …

Glycerol Overproduction by Engineered Saccharomyces cerevisiae Wine Yeast Strains Leads to Substantial Changes in By-Product Formation and to a Stimulation of …

F Remize, JL Roustan, JM Sablayrolles… - Applied and …, 1999 - Am Soc Microbiol
Six commercial wine yeast strains and three nonindustrial strains (two laboratory strains and
one haploid strain derived from a wine yeast strain) were engineered to produce large …

Activation of the DExD/H-box protein Dbp5 by the nuclear-pore protein Gle1 and its coactivator InsP6 is required for mRNA export

CS Weirich, JP Erzberger, JS Flick, JM Berger… - Nature cell …, 2006 - nature.com
Abstract The DExD/H-box ATPase Dbp5 is essential for nuclear mRNA export, although its
precise role in this process remains poorly understood. Here, we identify the nuclear pore …

[HTML][HTML] ADP regulates SNF1, the Saccharomyces cerevisiae homolog of AMP-activated protein kinase

FV Mayer, R Heath, E Underwood, MJ Sanders… - Cell metabolism, 2011 - cell.com
The SNF1 protein kinase complex plays an essential role in regulating gene expression in
response to the level of extracellular glucose in budding yeast. SNF1 shares structural and …

Effects of Furfural on the Respiratory Metabolism of Saccharomyces cerevisiae in Glucose-Limited Chemostats

I Sárvári Horváth, CJ Franzén… - Applied and …, 2003 - Am Soc Microbiol
Effects of furfural on the aerobic metabolism of the yeast Saccharomyces cerevisiae were
studied by performing chemostat experiments, and the kinetics of furfural conversion was …

2H and 13C metabolic flux analysis elucidates in vivo thermodynamics of the ED pathway in Zymomonas mobilis

TB Jacobson, PA Adamczyk, DM Stevenson… - Metabolic …, 2019 - Elsevier
Zymomonas mobilis is an industrially relevant bacterium notable for its ability to rapidly
ferment simple sugars to ethanol using the Entner-Doudoroff (ED) glycolytic pathway, an …

Dynamic responses of reserve carbohydrate metabolism under carbon and nitrogen limitations in Saccharomyces cerevisiae

JL Parrou, B Enjalbert, L Plourde, A Bauche… - Yeast, 1999 - Wiley Online Library
The dynamic responses of reserve carbohydrates with respect to shortage of either carbon
or nitrogen source was studied to obtain a sound basis for further investigations devoted to …